Some stem cell good news, stuff for debate, & cool pubs

in vivo reprogramming
Evidence of in vivo reprogramming in skin. "tissues were generated by converting one cell type (red: mesenchymal cells) to another (green: basal keratinocytes) within a large ulcer in a laboratory mouse model." Quote from Salk Institute caption. Image from Salk Institute.

Sometimes we could all use a jolt of good news and cool science.

Those of us in the stem cell field probably get tired at times of all the bad-ish, even if important news (like this from Michael Hiltzik of the LA Times) out there surrounding certain unproven stem cell offerings and also clinics that engage in all kinds of stuff ranging from off-beat shenanigans to really dark stuff.

Today’s post is focused mostly on the good news and exciting science. You can see past posts on good news in our stem cell arena here.

in vivo reprogramming
Evidence of in vivo reprogramming in skin. “…tissues were generated by converting one cell type (red: mesenchymal cells) to another (green: basal keratinocytes) within a large ulcer in a laboratory mouse model.” Quote from Salk Institute caption. Image from Salk Institute.

Below I’ve listed some upbeat headlines and also links to some intriguing research papers, but I couldn’t resist putting in a few more links to things that are not necessarily good news yet are interesting or spark conversations or debates.

Headlines

Kyoto Univ. team eyes clinical test of platelets derived from iPS cells

To Heal Wounds, Cells Time-Travel Back to a Fetal State

Stem cells show promise as drug delivery tool for childhood brain cancer

Officials Hope Indiana Will Become Leader In Regenerative Medicine

The latest worker benefit: Freezing stem cells in case they’re useful. Is it worth banking your cells?

Adult Cardiac Stem Cells Don’t Exist: Study Do adult hearts have stem cells?

Pubs

In vivo reprogramming of wound-resident cells generates skin epithelial tissue. For more on in vivo reprogramming see here. Also check out the cool image of in vivo regeneration sourced from the Salk, where this work was conducted.

Chromatin remodeling factor BRG1 regulates stemness and chemosensitivity of glioma initiating cells

Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration

Is there adult neurogenesis? The debate continues here in Cell Stem Cell piece. My perspectives piece on this from this spring.

Special Series: Transplantation of Stem Cells into the Eye

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