July 4, 2020

The Niche

Knoepfler lab stem cell blog

Month: August 2011

4 min read

With the bewildering amount of news about stem cells, how do we tell the difference between hype and hope? Although the words “hype” and “hope” only differ by one letter, sometimes it is hard to tell them apart in real life, but of course they are very different things. So how do we know when something is being blown way out of proportion (hype) and distinguish that from a very exciting advance in the field that almost seems like sci-fi it is so cool …Read More

2 min read

We have a running series on the Republican candidates for the GOP nomination for President for the 2012 Election. I blogged about Romney here, Huntsman here, and talked about Tex Guv Perry’s own stem cell transplant here. I also discussed the Republican field more generally in my podcast which you can listen to here or on iTunes. Perry just announced right now that he is running for President. Now, what if Perry became President? What would happen to science in America and specifically stem …Read More

4 min read

Periodically we do updates on the iPS cell field and now seems like a good time. Where do things stand? Here’s my top 5 list of action items for the iPS cell field in the coming year. 5.) Methods on the brain. A significant fraction, some would argue too high a fraction, of iPS cell papers will be methodological in the coming year. Depending on the author, some of these are likely to be published in very high profile journals. Will any be truly …Read More

2 min read

Recently I polled my readers on how they make iPS cells and what the best method is in their opinion. The surprising results to date are above. The first thing that is striking is how dominant the Yamanaka method remains after 5 years. Despite scads of papers reporting new methods that are supposedly better in various ways than Yamanaka’s method, nearly half (46%) of all respondents either use the method or felt it was the best. Also interesting is that the Thomson method (used …Read More