May 29, 2020

The Niche

Knoepfler lab stem cell blog

Month: March 2013

3 min read

Five legends and a blogger walk into a bar together. The bartender asks the first legend “What can I get for you?” The legend orders their drink. The bartender eventually serves up drinks to all five legends and turns to the blogger, “And what can I get for you?” The blogger replies, “Do you have Wi-Fi? “…..and a beer.” I’ve now been doing my stem cell blog for about 2 1/2 years. It started as an experiment and sort of took on a life of …Read More

3 min read

I recently interview Arnold Caplan, the father of the MSC field, and published part 1 of the interview (you can read it here). Today in part 2 we cover more topics of great importance related to MSCs including propagation, placebos, and patients as well as publishing. A hot topic in the stem cell world more generally, but especially in the MSC field is what happens to stem cells when they are grown in a lab. Many important questions are being asked. Are the propagated …Read More

1 min read

CIRM has indicated that the Institute of Medicine (IOM) recommended that CIRM provide funding for training and research on ethics and regulatory issues. In response to this recommendation and with the perspectives of various “CIRM funded researchers and other experts”, CIRM has responded with a new ethics & regulatory recommendation document. I have read it and am a big fan of this step by CIRM. The document outlines a number of key areas for consideration and important questions. The overall response to the IOM …Read More

1 min read

It has been a tough year for Korean stem cell biotech RNL Bio in my opinion. It is involved in litigation with former patients and its former partner, Celltex. It is also reportedly under investigation by the Korean Government for alleged stem cell smuggling. The stock of this publicly-traded company has also been battered. On Friday alone it reportedly plunged 15% (the maximum daily limit for a decrease). Thus, it seems likely to dive further on Monday. Reuters also reported that trading in RNL …Read More

2 min read

Would you want a GI specialist doing your heart surgery? How about a radiologist doing your brain surgery? I wouldn’t. So why then do so many patients accept that the doctor doing their stem cell transplant has no training in that area? I’m doing a series on eight simple reasons not to get an unlicensed stem cell treatment. Up to this point, I’ve covered four important reasons to pause before getting such a treatment: potential loss of insurance coverage for negative outcomes that could cost hundreds …Read More

3 min read

A few days ago I had a long, very enjoyable phone conversation with the father of the mesenchymal stem cells (MSC) field, Dr. Arnold Caplan. Dr. Caplan is Professor of Biology, Director Skeletal Research Center at Case Western. He coined the phrase “mesenchymal stem cell” in the late 1980s. I’m going to break the interview into 4 parts. Today is Part 1, focused on the history, nomenclature, and properties of MSCs. I learned a lot to put it mildly from talking with him. (See …Read More