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Transdifferentiation makes a major advance: direct reprogramming of fibroblasts to oligodendrocyte progenitors - The Niche
Back-to-back papers (here and here) in Nature Biotechnology report the transdifferentiation (now often simply referred to as “direct reprogramming”) of plain old fibroblasts into brain cells called oligodendrocyte progenitor cells (OPCs). OPCs are a remarkably useful kind of brain cell that generates myelin, which insulates nerves. OPCs are thought to have great therapeutic potential for … Transdifferentiation makes a major advance: direct reprogramming of fibroblasts to oligodendrocyte progenitors Read More »
Professor Paul Knoepfler, Ph.D.