July 14, 2020

The Niche

Knoepfler lab stem cell blog

Month: February 2014

1 min read

What will the future bring for STAP stem cells? Let’s look into a stem cell crystal ball. We are now one month out from the original publication of the papers. When we are three or six or twelve months out from their publication will independent labs have succeeded in replicating the method? It’s possible, but it is also perhaps equally likely that that won’t have happened. What about the papers–will they be corrected and that’s it? Or could they face something as severe as retraction …Read More

5 min read

I asked Dr. Teruhiko Wakayama, who goes by Teru to those who know him, if he would be willing to do a Q&A on the STAP stem cell situation. Teru was senior author on the STAP stem cell Nature letter on chimerism, but was not a senior (note this is a correction from an earlier version of this post) author on the other STAP paper, the Nature article on the production of STAP stem cells. Teru kindly agreed to my invitation. He responded straightforwardly to what I thought …Read More

2 min read

I don’t know about you, but this whole STAP stem cell thing has got me kind of bummed out. Last night I was thinking to perhaps stop blogging about it as the situation turns darker, but it seems like it wouldn’t do any good to ignore it. The ostrich with head in the sand approach won’t work here (image from Wikipedia). Heads up, eyes and minds open, and push for dialogue. I’m continuing to reach out to the scientists involved to talk and keep …Read More

4 min read

An FDA committee began a meeting yesterday that continues today to consider permitting new assisted reproduction-based “3-parent” technology that could address mitochondrial disorders, a serious human health problem. The technology also raises complex health issues of its own and invokes ethical questions. The goal of the FDA meeting is articulated this way: “the committee will discuss oocyte modification in assisted reproduction for the prevention of transmission of mitochondrial disease or treatment of infertility.” The technology, given the informal moniker of “3-parent” reproduction by some, …Read More