July 13, 2020

The Niche

Knoepfler lab stem cell blog

Month: March 2015

4 min read

The big stem cell news already this week is the acquisition by Fujifilm of Cellular Dynamics International (CDI) for a whopping $307 million dollars or about $16.50 per CDI share. You can read the press release here. Update: The entity is now known as Fujifilm Cellular Dynamics. It was less than two years ago that CDI did its IPO with an initial offering of about $46 million. Fujifilm reportedly has a multibillion-dollar war chest for buying into the life sciences sector and a growing interest in regenerative …Read More

2 min read

If you work in academia and on grants, hen you might have been getting that grant Möbius strip, hamster wheel, Groundhog Day kind of feeling… The funding rate for the key so-called “R01” NIH laboratory biomedical grant has never been lower. In the long run, R01s are crucial to the everyday running of most biomedical labs in America. (Update: I highly recommend you check out this grantsmanship website for useful, practical information.) It might take 10-15 tries to get one grant if one assumes all …Read More

2 min read

Discussion of concerns over heritable human genetic modification has spiked in 2015. This dialogue is a good thing, but is it in a sense too late? Are genetically modified (GM) people a foregone conclusion? Rumors are swirling that upwards of four papers reporting production of GM human embryos are in various stages of review at high-profile journals, sparking a sense of urgency for some kind of steps to deal with this new reality. Could these papers report germline correction of the CTFR mutation in cystic fibrosis …Read More

6 min read

By Jane Langille A few weeks ago, I wrote to Dr. Paul Knoepfler after reading his book Stem Cells: An Insider’s Guide because I was intrigued by his stem cell theory of aging. I wondered if his theory might mean that someone who mobilized and donated hematopoietic cells might be shortening their own lifetime supply. After exchanging emails about my daughter’s experience, he invited me to contribute a guest blog as he felt that the complexity of her experience as a donor and the questions …Read More