September 27, 2020

The Niche

Knoepfler lab stem cell blog

Month: November 2016

2 min read

It takes a great deal of courage to participate in a clinical trial, patients who make that choice are heroes in my book and one such hero with stem cells was Ted Harada who had ALS. Sadly, Ted passed away from a brain tumor called glioblastoma last month. When enrolling in a trial, you just never know if it will be beneficial or even be safe, and this is especially true of early phase clinical trials. As a result, it takes guts to be a …Read More

3 min read

I’m hearing more questions from the community about alleged harm from stem cell clinics selling stem cells for a number of vision-related conditions and some concerns include the so-called SCOTS study. I first blogged about SCOTS early this year and back then I myself had questions too. Some commenters then raised concerns or questions about SCOTS in weighing in on that post. In my opinion SCOTS is almost certainly not a traditional FDA phased clinical trial, which raises issues right from the get go. I’m not aware …Read More

1 min read

Will Trump trump the FDA? Our President-elect recently released his health care policy agenda and it looks like the FDA is a target in terms of reducing oversight. Over at the Washington Post, Carolyn Johnson has a nice article on this development. One point in the agenda in particular has caught people’s attention as potentially the key indicator of what is to come for regulatory oversight of biomedical products: “Reform the Food and Drug Administration, to put greater focus on the need of patients for new …Read More

2 min read

I appreciate fun linguistic approaches to explaining science such as a good science metaphor and I use them myself at times, but sometimes these end up risking doing much more harm than good. The best or should I say worst example I’ve heard recently is referring to a growth factor called BDNF as “Miracle-Gro for the brain”. What the heck? BDNF is the acronym for brain-derived neurotrophic factor. It is a growth and trophic factor that has the exciting potential to induce helpful changes in the …Read More