September 26, 2020

The Niche

Knoepfler lab stem cell blog

Month: September 2017

7 min read

Two new FDA inspection reports called 483s provide fresh insights on a stem cell clinic, the network of clinics that it belongs to, and adverse events in patients. These reports detail issues the FDA found at the stem cell clinic California Stem Cell Treatment Center and its parent chain of clinics, Cell Surgical Network. The latter is an affiliated group of dozens of stem cell clinics across the U.S. generally marketing experimental adipose (fat) stem cell therapies, sometimes called “stromal vascular fraction” or SVF). As …Read More

6 min read

Right now the FDA has a big fat stem cell conundrum on its hands. The agency is faced with a tough dilemma as how to deal with fat (adipose) stem cell products and the large number of businesses who sell them. Are fat/adipose stem cells a drug or not? If yes, what does the FDA do about the hundreds of clinics currently marketing them without approval? If not, then how does the agency reconcile that with its past statements and even words this year under …Read More

2 min read

Science hype is one of the more troublesome issues in our field today especially at its interface with the media, and unfortunately a ‘great’ example of that came this past week in a headline from the Daily Mail on the new CRISPR of human embryos paper from Kathy Niakan’s group in the UK. Although Niakan’s group was generally appropriately cautious in their new Nature paper about potential clinical implications of their work and didn’t hype possible reproductive use of CRISPR in humans at all, they …Read More

2 min read

If you garden long enough you may start to see some cool critters. We had an unusually wet winter and very hot, dry summer here in Davis, CA. Maybe it’s coincidence, but the range of creatures in my garden seems different. For instance, I’ve been seeing much bigger dragon flies this year and a lot more lizards. A few days ago I saw a very unusual lizard (see above). What a tail! What gene expression makes that unusual tail? The reddish color of the …Read More