Month: November 2017

Twenty years later: would this dataholic still go to grad school?

Mark Kamps Paul Knoepfler mentor

Grad school…would you do it all over again if you could jump in a time machine? It’s hard to imagine, but it was 24 years ago that I started at UCSD as a graduate student. Think how different the world was in 1993. Now almost a quarter century later, the world of science is very …

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Extraordinary epidermis regeneration in child via combo stem cell-gene therapy

Hirsch-et-al-epidermal-regeneration-Fig.-2a

Epidermis regeneration is an important approach to helping patients with a variety of serious skin problems that can arise due to genetic conditions or injuries such as severe burns. An exciting new Nature paper reports epidermis regeneration on a strikingly large-scale. The child who is the subject of the study suffers from a sometimes fatal genetic …

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7 tech hurdles to human germline CRISPR

Human-crispr-challenges

Human germline CRISPR raises major bioethical considerations, but what about technical issues? Setting aside the many ethical issue about the general idea of human modification itself, could this really work? Yes in theory it could, but there are some very tough technological challenges that could and likely would cause failures or unacceptable outcomes at many steps …

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Weekend Stem Cell Reads: Naked mole rats, geckos, brain gel, & more

naked-mole-rats

Here are some stem cell reads for the weekend, ranging from media to research articles. TGIF! What are your stem cell or other science weekend reads? Let’s start with how difficult it is to make IPS cells from naked mole rats! Naked Mole Rat Cells Have a Stable Epigenome that Resists iPSC Reprogramming. It takes more than …

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Australia takes big step to curtail dangerous stem cell clinics

Australia-stem-cell-clinics

The ability of for-profit stem cell clinics to pitch unproven, risky stem cell offerings to patients may soon get much tougher in Australia. The country’s Therapeutic Goods Administration (TGA), which has some similar responsibilities there as the FDA does here in the U.S., announced planned new reforms that’ll put stem cell clinics under more scrutiny and more …

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