January 22, 2021

The Niche

Trusted stem cell blog & resources

Month: July 2018

2 min read

A much-anticipated induced pluripotent stem (IPS) cell trial for Parkinson’s Disease reportedly will soon launch led by Professor Jun Takahashi. The news broke on Yahoo Japan, which included an unusual number of appropriately sober statements regarding the trial, even though it is an exciting trial as well, compared to most media stories on stem cells. Parkinson’s Disease is a result of a loss of dopaminergic neurons in the brain so it is a particularly attractive target disease for stem cells, which can be readily …Read More

3 min read

It’s a funny thing how having this blog can provide insights into unexpected stem cell events and news going on around the world such as, most recently, action by the government of Romania on stem cell firms there for alleged “dirty practices”, news that as far as I know has only been reported in Romanian. How did I learn of this? I know a small amount of Romanian myself, but on my site I have a project called SCOPE, which provides a basic stem …Read More

2 min read

I’m becoming increasing convinced that patient suits against stem cell clinics are going to have strong impact, including based on the new steps taken by a particular law firm. For background, I’ve written extensively about these suits over the years and we’ve seen more recently that another academic group (Claire Horner, Evelyn Tenenbaum, Douglas Sipp, Zubin Master) has published a paper on the suits. The law firm stepping up against clinics is GRYC or Grossman, Roth, Yaffa, and Cohen. They not only have and continue to represent …Read More

2 min read

When you get an FDA warning letter (like if you are a non-compliant stem cell clinic) you generally aren’t feeling too well after reading it, but now there’s an extra thing to worry about according to the FDA. A fake FDA warning letter. Apparently 3-dozen or more of these fake FDA warning letters sparked complains to the agency. Reporter Stephanie M. Lee over at BuzzFeed Science was on this too. First thought: maybe it’s kind of like those phone messages being left all over …Read More

4 min read

It’s an odd confluence of events this week that (A) the Nuffield Council, an ethics think tank, gives a thumbs up in a new report to heritable human genetic modification that would probably include using CRISPR in the same week that (B) a new paper reports that CRISPR can cause unpredictable genomic damage and several other concerning reports about possible CRISPR technology side effects or challenges have come out in the last few months. Talk about bad timing. They would probably counter my intro paragraph by saying …Read More

4 min read

If it seems to you like dramatic cautionary tales about CRISPR accompanied by all sorts of media are coming at us more frequently, it’s not your imagination. In the latest yesterday, it was reported in a new paper led by Allan Bradley that CRISPR-Cas9 results in sometimes large-scale chromosomal lesions at or even away from the target locus. The media have really sunk their teeth into this one, just as in past situations where CRISPR has reportedly encountered anything from bumps in the road to …Read More

3 min read

What’s Australia like from the science to the country? I enjoyed the ISSCR2018 Annual Meeting in Melbourne on stem cells and regenerative medicine a few weeks back(here is a post on the some of the notable science from Day 1), but I also got a chance to get to know Australia a bit too. Below I have listed 7 observations about Australia interspersed with some fun pictures. First, I had a very positive impression of Australia and its people. The country is interesting and gorgeous. The …Read More

3 min read

Over the weekends I try to catch up on more diverse reading and sometimes come up with a list of stuff I want to get to during this time, but I also put together weekend reads usually on Fridays as a kind of TGIF on The Niche for the wider audience here. So here’s the weekend reads for this Friday the 13th including some wacky stuff at the end. Anti-Aging efforts got some play in the media including this LA Times piece. Here’s the …Read More