August 7, 2020

The Niche

Knoepfler lab stem cell blog

Month: November 2018

2 min read

I’ve been hearing more recently about something called the American Academy of Stem Cell Physicians (variously AAOSCP or AASCP). Its name has the sound of an organization like some traditional medical academy such as the American Academy of Internal Medicine, but my sense is that this is a totally different kind of beast. People have been asking me what’s the story with it. What is its mission? I did find something akin to a mission scrolling down on their homepage: “The American Academy of …Read More

4 min read

The stem cell clinic industry selling unapproved “therapies” is ubiquitous and yet somehow still growing it seems. Many of us are encountering more of them including via ads and the clinics are basically all over the place. What should someone do if they see a stem cell clinic that is particularly concerning? A lot of people are asking me this question lately. There are a variety of options depending on your level of concern, but below is a guide to possible actions you can …Read More

3 min read

When you think of an ecosystem, do you imagine something like a forest or jungle full of different organisms? I usually do, but over the last few years I’ve also been thinking about this concept in a different way. I’ve been viewing the broad stem cell arena as an ecosystem. In that spirit, I’ve recently published a new paper in Regenerative Medicine that delves into the idea of a “stem cell ecosystem”. This system has many parts and if you view it historically it …Read More

2 min read

Magenta Therapeutics is a biotech company with a portfolio including stem cell products. Their most well known investigational drug product is an expanded umbilical cord stem cell product called MGTA-456, an “ex-Novartis” product. Magenta just released new trial data on MGTA-456, which I see as a case of good news-bad news, and investors seem to have had a similar reaction. The company describes MGTA-456 as, “a first-in-class allogeneic stem cell therapy consisting of a single umbilical cord blood unit expanded with an aryl hydrocarbon …Read More