August 14, 2020

The Niche

Knoepfler lab stem cell blog

Month: April 2019

5 min read

This post is a recap of some major points of Game of Thrones Season 8 Episode 3 and The Battle of Winterfell. Before you go on, there are tons of SPOILERS ahead so stop and leave now if you don’t want to see them. Really, many SPOILERs so go away if you don’t want to see them! Spoilers are coming… (Note that I’ve provided an update on this post after sleeping on the episode, see more below). In the lead up to this middle …Read More

4 min read

Trying to make a CRISPR baby any time soon would be a really bad idea. How bad? Last December 3rd I penned a piece for STAT News arguing for a moratorium on the heritable use of CRISPR in humans. This potential future, radical application of “gene editing” is now often colloquially referred to as “CRISPR babies”. Read that piece for the reasons behind my thinking and the risks involved in leaving the door open to using CRISPR to make people. Of course, this was …Read More

2 min read

My daughter Julie and I have written a book together entitled,  “How to Build a Dragon or Die Trying, A satirical look at cutting edge science.” The book will be out sometime in June most likely. This is a very different kind of book than my first two, Stem Cells: An Insider’s Guide and GMO Sapiens. In How to Build a Dragon we, first of all, take a satirical tone as highlighted by the subtitle. We are somewhat poking fun at science hype in …Read More

2 min read

It’s been a cool week for stem cell and other associated kinds of research. In this post I have a series of links to a variety of interesting developments and papers. Gene therapy cures bubble boy infants. William Wan over at the WaPo on this good news. Nope, this wasn’t done with CRISPR, but rather with a viral transgene approach (not TALENs as I mistakenly had originally written here). “The pigs were dead. But four hours later, scientists restored cellular functions in their brains”. This …Read More