Month: July 2020

Mid-week rec reads: plague paleogenomics, bats, art, get new skin, & more

The-Dancers-III-IV-Marguerite-Humeau

I’m doing an experiment today to see if people enjoy a mid-week splash of a few Wednesday recommended science reads and the first one collides with art. You can see Sunday’s recommended weekly reads here too. Also, be sure to visit our Facebook page if you have a moment and please like our page if …

Mid-week rec reads: plague paleogenomics, bats, art, get new skin, & more Read More »

Q&A with Roxland on stem cell clinic suits by Iowa & Nebraska

beth-roxland

I wrote last week about the Nebraska and Iowa state Attorney Generals filing lawsuits against stem cell clinic firms and three individuals also named as defendants. Although I went into detail about the individuals including leader Travis Autor and the firms, I didn’t yet go into much depth on the state lawsuits themselves in that …

Q&A with Roxland on stem cell clinic suits by Iowa & Nebraska Read More »

Weekly reads: FDA news, goosebump stem cells, MSCs, autophagy

Levy-et-al-MSCs-Science-Advances

Ready for the latest recommended weekly reads in the world of stem cells and the regenerative medicine space including a bunch of important new FDA posts & changes? This post has quite a lot on the FDA since it had a very big week with several new items of major importance to the cellular and regenerative …

Weekly reads: FDA news, goosebump stem cells, MSCs, autophagy Read More »

2 State AG’s sue ‘Stem Cell Centers’ clinics including for alleged fraud

Travis-Autor

Some readers suggested earlier this year that I look into a clinic firm called ‘Stem Cell Centers’ with its owner Travis Autor. I didn’t have time to do much since I’ve been very busy in the lab before the state Attorney Generals of Iowa and Nebraska sued them based on a number of allegations including …

2 State AG’s sue ‘Stem Cell Centers’ clinics including for alleged fraud Read More »

Weekly reads: ‘junk DNA’, COVID chaos, CRISPR CasΦ, & postdoc opps, more

Retroviral-genes-Junk-DNA-NIHsmall

Here are our weekly recommended regenerative medicine and other notable science reads including a few things on COVID. It’s been quite an interesting week. “Junk DNA” is not so junky, role in differentiation NIH scientists showed how ancient retroviral genes, or “junk DNA”, may play a role in helping stem cells decide to become neurons. This …

Weekly reads: ‘junk DNA’, COVID chaos, CRISPR CasΦ, & postdoc opps, more Read More »

New Mesoblast “COVID kid” stem cell study

Dr-Fred-Grossman-CMO-Mesoblast.

The biotech Mesoblast is starting an expanded access study of its stem cell product for kids with a severe offshoot of COVID-19. The cellular drug in this case is remestemcel-L (more below). While most children fare better than adults in dealing with COVID-19, the rare subset of kids with COVID-19 for this study have more severe …

New Mesoblast “COVID kid” stem cell study Read More »

Reciprocal CRISPR gene editing in pediatric glioma: defining mechanisms & testing drugs

reciprocal-CRISPR-mutant-H3.3

My lab’s new paper in Communications Biology focused on high-grade pediatric glioma that have mutant histone variant H3.3 and we did something fairly novel that we are calling reciprocal CRISPR. Kids with these tumors have a near zero survival rate within a few years of diagnosis so we as a field desperately need something new to give …

Reciprocal CRISPR gene editing in pediatric glioma: defining mechanisms & testing drugs Read More »

OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads

EMBO-J-2020-Fig-3b-Salazar-Roa-et-al

What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding …

OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads Read More »

Groundbreaking Organoid Vision Clinical Study: Takahashi Q&A

Mandai-et-al-Stem-Cell-Reports-2017

Organoid based clinical trials are still rare and a Clinicaltrials.gov search for such organoid work largely brings up in vitro studies. A new clinical study in Japan where organoid material will actually be transplanted into patients is causing a lot of excitement. Organoid clinical trial Masayo Takahashi (高橋 政代) is a pioneer in stem cell-based …

Groundbreaking Organoid Vision Clinical Study: Takahashi Q&A Read More »

সস্য কোষ (স্টেম সেল) কাকে বলে? What are stem cells in Bengali

Dr.-Anwesha-Ghosh

Note that this is post “সস্য কোষ (স্টেম সেল) কাকে বলে?” in Bengali is one part of our “Stem Cells Not Lost in Translation” series. You can see the full series of our stem cell white paper in the other 34 languages here. সস্য কোষ (স্টেম সেল) কাকে বলে? মানবদেহে শত শত বিভিন্ন ধরণের কোষ …

সস্য কোষ (স্টেম সেল) কাকে বলে? What are stem cells in Bengali Read More »