November 23, 2020

The Niche

Knoepfler lab stem cell blog

Month: September 2020

4 min read

In my view, it seems likely that the FDA has opened a big can of worms by starting to clear the COVID-19 trials and programs of for-profit stem cell clinics and other related firms. OK to Stemedica trial The FDA just approved another such effort, this one by the firm Stemedica. You can read more about previous such COVID-19 cell therapy clearances for the unproven clinic firms Celltex and GioStar here. The Stemedica trial is similar to some of the other cell therapy efforts for …Read More

6 min read

Drugs that restore the shape of the errant protein behind cystic fibrosis (CF) have, over the past eight years, helped the majority of patients, who have certain mutations. Gene-corrected stem cells might offer a “mutation agnostic” option to CF. CF results from a glitch in a glycoprotein with the unwieldy name “cystic fibrosis transmembrane conductance regulator”, or CFTR. The proteins normally fold into channels that regulate the flow of ions into and out of cells, controlling the balance of water and salts in linings …Read More

2 min read

Does time seem somewhat warped to anyone else in 2020 even without having  had COVID, which could alter brain function? It just seems like with everything going on that time simultaneously both drags and zooms by this year. One sort of reassuring element is that papers keep on being published so we can enjoy cool new science. There’s one last chance to win a bundle of free stem cell and regenerative medicine swag by filling out our reader survey here. It only takes a …Read More

2 min read

Back at the beginning of the year I surveyed you readers here on The Niche about the future of CIRM and whether California voters would approve more funding for it in November. That funding effort is now on the ballot as Proposition 14. A month earlier late in 2019 in my yearly 20 predictions for the stem cell and regenerative medicine field I had prognosticated that we California voters would narrowly approve more funding for the California Stem Cell Agency. You can see that …Read More