Year: 2020

Polls: will California approve Prop 14 to fund CIRM again? Should it?

Knoepfler-The-Niche-stem-cell-blog-predictions-2020

Back at the beginning of the year I surveyed you readers here on The Niche about the future of CIRM and whether California voters would approve more funding for it in November. That funding effort is now on the ballot as Proposition 14. A month earlier late in 2019 in my yearly 20 predictions for …

Polls: will California approve Prop 14 to fund CIRM again? Should it? Read More »

New research on CRISPR gene-editing in stem cells, infographic

CRISPR-infographic-stem-cells_small

As a pivotal advance in the gene-editing field and timeline, CRISPR continues to be utilized for research on stem cells and human diseases. Today, I will explain some of the most notable recent findings in the stem cell-CRISPR field. To start things off, I have also created an infographic that briefly explains what CRISPR-Cas9 is, …

New research on CRISPR gene-editing in stem cells, infographic Read More »

Seth Rogen is a stem cell pitching Prop 14 for CIRM in funny new video

Stemmy-Stem-Cell-Seth-Rogan-for-CIRM

Should California’s Stem Cell Agency, more widely known as CIRM, get another round of funding from us California voters? I believe the answer is yes and I endorse Proposition 14, which would provide the funding for CIRM to translate dozens of clinical trials into some proven new stem cell-based treatments in the coming decade. However, …

Seth Rogen is a stem cell pitching Prop 14 for CIRM in funny new video Read More »

Recommended reads: Bee brain, COVID, from Russia with stem cells, pubs

Reprogramming-roadmap-reveals-route-to-human-induced-trophoblast-stem-cells

Reading to them was one of my favorite things to do with my kids when they were little, but it’s a long way from Goodnight Moon to this week’s list of recommended reads, although “bee brain” may have got their attention. Please take a minute to complete our The Niche reader survey for a chance …

Recommended reads: Bee brain, COVID, from Russia with stem cells, pubs Read More »

Georgia AG sues clinics & owner Justin Paulk

Justin-Paulk-a-defendant-in-suit-by-Georgia-AG-for-alleged-stem-cell-clinic-violations.

More states have taken action against stem cell clinic-related firms in the past year than ever before and now we can add Georgia to the list. Georgia adds to growing list of state AGs suing stem cell clinics The George Attorney General Chris Carr filed suit against several related firms (going by various names over …

Georgia AG sues clinics & owner Justin Paulk Read More »

Recommended reads: PSC, COVID, FDA pledge, sci jobs

Sarthy-et-al-eLife-2020-Fig-2

When you sit down to read science on the weekends lately, assuming you are not primarily a COVID-19 researcher, how much COVID stuff seeps into your reading? As I was going over some of this year’s recommended weekly reads posts here on The Niche, I’ve realized that an increasing amount of COVID-19 research has joined …

Recommended reads: PSC, COVID, FDA pledge, sci jobs Read More »

Enter the Niche Reader Survey for chance at free stem cell swag

knoepfler-stem-cell-t-shirt-225x3001

It’s helpful for me to learn about the readers of this blog The Niche in terms of who you are and your backgrounds. Because some people may want to vote more than once on the types of posts they like the most, I’ve allowed re-voting on that poll. Free stuff Those who participate and leave …

Enter the Niche Reader Survey for chance at free stem cell swag Read More »

New human genome editing (HHGE) academy report: solid, but key gaps

The-International-Commission-on-the-Clinical-Use-of-Human-Germline-Genome-Editing-HHGE

Something called, “The International Commission on the Clinical Use of Human Germline Genome Editing” has issued a new report on heritable human genome editing (HHGE). The Commission was convened by the U.S. National Academy of Medicine, the U.S. National Academy of Sciences, and the U.K.’s Royal Society. This post is my initial take on the summary of …

New human genome editing (HHGE) academy report: solid, but key gaps Read More »

Recommended regenerative medicine reads: COVID-19 updates, Cornea Fix, Pubs

2019nCoV-NP-cardio-myocytes

Another week and more great papers and interesting news in the regenerative medicine sphere including COVID-19 updates, stem cells for vision, and more. Rebuilding Corneas With Stem Cells Stem cell-based regenerative medicine arguably has shown the most promise for vision loss. A PR from Massachusetts Eye and Ear says: Doctors rebuild damaged corneas using patients’ …

Recommended regenerative medicine reads: COVID-19 updates, Cornea Fix, Pubs Read More »

CAR-T cells review: cancer & a critical look at possible uses in aging & COVID-19

CAR-T-cell-infographic

Introduction to CAR-T cells CAR-T cells are an exciting cutting-edge technology that has been garnering great interest including in the stem cell field. Potential therapeutic uses of CAR-T, which stands for Chimeric Antigen Receptor T-Cells (CAR-T), are being studied in clinical trials as immunotherapies to potentially fight cancer as well as many other diseases by …

CAR-T cells review: cancer & a critical look at possible uses in aging & COVID-19 Read More »