Search Results for: "stem cell niche"

Weekly reads: Melton leaves Harvard, Fuji, BBC blunder, stem cell niche, more

Senolytics restore the stem cell niche in the brains of mice. Fatt, et al. Stem Cell Reports 2022.

Sometimes a post here on The Niche (named after the stem cell niche) sparks a debate between expert stem cell researchers and often that gives much more depth to a topic. Such was the case with my post this week on where things stand with stem cell therapy for heart disease. It led to a …

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Recommend reads: stem cell niche, Georgia & FTC on clinics, more

Georgia AG Chris Carr

This blog is called The Niche so publications on the stem cell niche often catch my eye even if that’s not something my own lab directly works on much. So today’s recommended reads will start with two papers on the stem cell niche. The first one focused on the niche  gone wrong. The stem cell …

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Weekly reads: our new brain tumor paper, levitation, dear doctor, Japan, more

brain tumor, H3.3 K27M, ASCL1

There’s nothing quite like getting a new paper out as a scientist running a research lab so this week we can celebrate our new pediatric brain tumor study. I’ll start the weekly reads with that paper. Of course, getting new grants is amazing too but there’s more of a feel of completion after a paper …

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What is Matrigel, why a shortage, & alternatives?

Matrigel

Stem cell research relies on some unusual reagents at times including a cell culture product called Matrigel. One of the challenges with such reagents is that if they suddenly are back-ordered it could bring some research to a halt. Matrigel has been in short supply for the last year or so. These products also tend …

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Recommended reads: senolytics, cow iPS cells, big CIRM royalty

Senolytics Steve Horvath

When we hear the word senile we might think stereotypically of an older person who has cognitive impairment, but some argue that senility can apply to cells too as they age and that such cells can be targeted by drugs called senolytics. Unfortunately, the supplements industry has picked up on this idea to sell iffy …

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Weekly stem cell reads: pending FDA verdict, blood vessels, RA

Cellular populations in the vascular wall, stem cell niche

Any day now we should get the verdict from the judge in the big stem cell clinic case here in California against Cell Surgical Network, et al. It seems that the FDA is waiting on this verdict before taking some major actions. If the judge rules against the agency it could throw the area into …

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Weekly recommended reads including asymmetric division & chromatin

Asymmetric division and chromatin

One of my favorite types of papers are those on stem cells and chromatin, and a new one in Current Biology caught my eye this week. My own lab website has the URL chromatin.com so that says something. You can also read more about our research here. Recommended reads: chromatin and stem cells, more Asymmetric …

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Weekly reads: cancer stem cells & other pubs plus a puzzler

kyu yum nature cancer stem cells niche

Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is …

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Weekly reads: stem cells for spina bifida & diabetes trials, pubs

arthur the dog helps test stem cells for spina bifida

It’s always great when there’s good news in the stem cell field and a new trial of stem cells for spina bifida here at UC Davis School of Medicine is very encouraging. So I’ll lead off with this story. Stem cells for spina bifida This pioneering work is led by Drs. Diana Farmer and Aijun …

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Scientist in the Garden: lessons for stem cells & science

tomatoes-Sacramento-e1496682448570

Here’s another edition of my posts over the years in my series ‘The Scientist in the Garden’. Can gardening teach us some important things about stem cells and about doing science more generally? Regular readers of this blog know that I am really into gardening and especially during the last 5 or so years I’ve been …

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