Search Results for: IPS cells

What are induced pluripotent stem cells or IPS cells & clinical prospects?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or IPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too, both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as drug screening. The …

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Stem cell reads: IPS cells, p53, mini-livers, baldness

stem-cell-grown-mini-liver-small

We’ve had another week of interesting stem cell news and papers. Here is an aggregate of the stem cell and regenerative medicine week that was. Stem cell therapy for baldness I’ve covered stem cells for hair loss for about a decade here on The Niche. While it seems like it’s taken a long time for …

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Cool Cat iPS cells & other notable stem cell pubs/news

Gur-Cohen-et-al.-Science-Figure-2b

Once or twice a month I do a post on notable stem cell publications and news, which often but not always include research on iPS cells. It’s sort of a recommended reads kind of post, but I often include one or two things that aren’t necessarily recommended exactly yet seem kind of surprising or novel …

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CRISPR to make IPS cells: review of new Ding lab paper

Liu-et-al-Cell-Stem-Cell-IPS-cells-2018

CRISPR and IPS cells are two of my favorite things so when they come together as in a cool, new paper from Sheng Ding’s lab, I’m excited to read it and curious as to what the scoop is. Since 2006-2007 when mouse and human reprogramming were first reported, many different methods have been explored to …

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New Yamanaka interview gives key insights into future of IPS cells

Nobel Laureate Shinya Yamanaka, the first to produce induced pluripotent stem cells

Where is the field of IPS cells going and how will this impact the overall field of stem cell-based regenerative medicine? Nobel Laureate Shinya Yamanaka, the discoverer of IPS cells, gave a really interesting recent interview to Nikkei that provides some fascinating insights into the future of this exciting technology that is now more than a decade …

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Weekend reads: ES cell research polls well, Gordie Howe, MS, IPS cells, and more

Gallup-Poll-stem-cells

Here are some headlines & articles worth a look and some thought on stem cell and biomedical science more generally. Gallup finds in a new poll that 60% of Americans surveyed find human embryonic stem celsl research “largely acceptable”. On the other hand human reproductive cloning is highly frowned upon, sandwiched in the “highly unacceptable …

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Pain in a dish? Drug testing bench to bedside with IPS cells

inherited-erythromelalgia

A new study on treating pain with a unique stem cell connection caught my attention. The paper was from a team at Pfizer led by Edward B. Stevens. Talk about bench to bedside, these researchers went all the way from patients to patient somatic cells to reprogrammed IPSC to neurons to model pain in a dish …

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Review of Mitalipov Nature paper: cloned ES cells vs iPS cells

NT-ESC

Just how good are human embryonic stem (ES) cells made by therapeutic cloning via nuclear transfer, with the successful technique first reported by the lab of Shoukhrat Mitalipov at OHSU last year? How do they compare to induced pluripotent stem (iPS) cells or traditional ES cells made from IVF embryos? A new paper in Nature directly tackles these …

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