October 22, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: arnold caplan

2 min read

Today is part of 4 (the last) of my interview with Dr. Arnold Caplan, MSC godfather and guru. You can read parts 1-3 of the interview here, here, and here. In this post I focus on my discussion with Caplan on translation of stem cells to patients and the FDA. During our conversation we talked about some of the challenges facing the efforts to make safe and effective stem cell therapies (including those based on MSCs) available to patients. Of course one key element is regulatory …Read More

2 min read

I recently had a phone interview with Dr. Arnold Caplan, the founder of the MSC field. You can read parts 1 and 2 of the interview here and here. Today’s post, part 3, is focused on clinical use of MSCs. I want to start off today’s post with a wonderful quote from Caplan: “All MSCs are good if no one screwed them up!” This statement by Caplan was in response in part to my asking about how different clinics handle MSCs is such dramatically …Read More

3 min read

I recently interview Arnold Caplan, the father of the MSC field, and published part 1 of the interview (you can read it here). Today in part 2 we cover more topics of great importance related to MSCs including propagation, placebos, and patients as well as publishing. A hot topic in the stem cell world more generally, but especially in the MSC field is what happens to stem cells when they are grown in a lab. Many important questions are being asked. Are the propagated …Read More

3 min read

A few days ago I had a long, very enjoyable phone conversation with the father of the mesenchymal stem cells (MSC) field, Dr. Arnold Caplan. Dr. Caplan is Professor of Biology, Director Skeletal Research Center at Case Western. He coined the phrase “mesenchymal stem cell” in the late 1980s. I’m going to break the interview into 4 parts. Today is Part 1, focused on the history, nomenclature, and properties of MSCs. I learned a lot to put it mildly from talking with him. (See …Read More