Search Results for: prc2

Weekly reads: PRC2, 2 weird bits of news, pubs, COVID stem cell hype

PRC2 lineage commitment

I’d say the paper of the week is on how PRC2 mediated H3K27me3 can in some sense replace elements of DNA methylation to repress. Very cool. Here it is: Sex-specific chromatin remodelling safeguards transcription in germ cells, Nature. Weird stuff In a merger of opposites, City of Hope to buy Cancer Treatment Centers of America …

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Weekly The Niche Reads: tooth repair, PRC2, beach pics

brandts cormorant jumping sm

I managed to escape to do some hiking along the coast so I’m behind on my weekly reading and I’m just getting back here on The Niche. Here are some articles I’m hoping to catch up on in coming days including an interesting overview of stem cells for tooth repair. I sometimes have a wistful …

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Recommended reads: COVID-19 updates, FDA stem cell nod, PRC2, more

Fig.-3d-Rai-et-al-Nature-Communications-2020

Today’s post is the latest edition of my weekly recommended reads, which this week include Fate Therapeutics, COVID-19 updates, AAMC, and more including some great pubs such as one on 2 modes of PRC2 function. Also check out this handy resource: Helpful 2020 List of Stem Cell Journals and this blast from the past post of 10 …

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OCT4-SOX DNA dance, PRC2, a noisy competition & more cell weekly reads

EMBO-J-2020-Fig-3b-Salazar-Roa-et-al

What’s new in the stem cell, cell therapy, and regenerative medicine world as well as biomedical science more generally including cancer? There’s quite a bit of news as reflected in media pieces and new pubs. Today’s post is focused on pubs that just came out. For last week’s recommended reads see here. Oct4-Sox2 Nucleosome Binding …

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Is DNA methylation destiny? Diving into new epigenetic clock research

I’ve been thinking more about the steady stream of epigenetic clock research out there.  How convincing is the research on such clocks? Do they tightly relate to human biological age?  The related notion of turning back such hypothetical clocks to reverse aging is exciting but controversial. It doesn’t help that some are hyping all of …

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Are immortal jellyfish actually mortal?

immortal jellyfish

About ten years ago I ran across the organism called the immortal jellyfish. Luckily I didn’t get stung because it wasn’t an in-person encounter like while swimming. Rather, I came upon the idea that these guys lived forever. Someone was even selling an immortal jellyfish extract. They claimed it would reverse aging in people. That …

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Histone code series: H3K27me3 & H3K27ac functions & roles in diseases like DIPG

ASCL1 in K27M tumors, H3K27me3 loss

Histone proteins such as histone H3 are often popping up in science writing and news sometimes includes specific modified forms of H3 including one that we scientists call H3K27me3. What is in this article What is H3K27me3? | The histone code | H3K27ac and H3K27me3 function | H3K27 and human disease | References The goal of today’s post …

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Vote for Screamers awards for worst science hype of the year: Gorilla Glue, COVID, diabetes ‘cure’, more

The Screamers Science Hype Awards.

The amount of biomedical science hype out there is mindboggling at times, but some media or other items really take the cake for being exceptionally bad. Today’s post highlights the worst of the year 2021 as the candidates for my annual The Screamers science hype award. Click on the link in the previous sentence to …

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Weekly reads: CRISPR’d marsupial, outpatient recovery post stem cell transplants, Parkinson’s, pubs

CRISPR'd baby opossums.

This edition of The Niche weekly reads has a bit more good news than usual including on stem cell transplants. It’s nice to see positive developments like some recipients of hematopoietic stem cell transplants being able to stay at home afterwards. Also, a reminder. You have until July 31 to enter our stem cell video …

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Weekly reads: court case, cancer stem cells, skin, pluripotency, & more

chen et al fig 1e nat comm 2021 phc1

This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally …

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