Aging

4 possible roles for stem cell therapy besides cell replacement

stem-cells-drug-delivery

Historically, the main route of proposed healing via stem cell therapy was cell replacement. In this way of thinking the transplanted cells engrafted (took up home) in the patient’s tissue and replaced dead or diseased cells. However, interest continues to grow in other possible modes of healing by stem cells that don’t rely on cell …

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Anti-aging and the billionaires young blood & stem cell club

Old-man-getting-young-bloodSeason-4-episode-5-of-Silicon-Valley-22Blood-Boy22, stem cells anti-aging

What is the Billionaire’s blood & stem cell club and how does one get into that? The focus of what I’m satirically calling this “billionaire’s club” is on anti-aging and prolonging life. If you have a lot of money and are willing to take risks on yourself toward some specific goal such as staying young …

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TGIF weekend reads: senolytics, new CRISPR, stem cells, & 3 wacky things

Mulas-et-al.-Development

Over the weekends I try to catch up on more diverse reading and sometimes come up with a list of stuff I want to get to during this time, but I also put together weekend reads usually on Fridays as a kind of TGIF on The Niche for the wider audience here. So here’s the …

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Stem cell news update: the good, the bad, & the weird

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With stem cells there’s always all kinds of developments and news every week or even every day. Here is an assortment in no particular order of some of the latest news including some across the spectrum including weird and sometimes stuff. The linked phrases are often the actual headlines of the media pieces. New CIRM …

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Aging: can we grow new brain cells as adults?

Cell-Stem-Cell-Boldrini-et-al.-new-brain-cells

Can we humans grow healthy new brain cells as adults and during later aging? The answer to this question is a big deal because it could have major impact on aging. Those hoped-for new brain cells could keep our brains functionally younger. Who doesn’t want to slow down the aging of their brain, right? Slowing …

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Can stem cells really fight aging & if so, how?

stem cells aging

If you want to fight aging, should you turn to stem cells? Does the idea of stem cells to battle getting old even make any sense? The answer is, “it depends.” It’s a really interesting area conceptually and technically for stem cells. A theory. There is evidence that things that happen to our endogenous stem …

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Stem cells for the flu? Pondering PR email, frailty data from Longeveron

Tompkins-Figure-2A

Stem cells for flu? For me, that idea is new. Some months back there was buzz about the stem cell biotech Longeveron related to its report on early trial data on testing infusions of mesenchymal stem cells for frailty in the aged. Frailty that pops up in some aging folks can manifest in a variety …

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Young blood as anti-aging fountain of youth: hype or hope?

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Imagine an old man and a teenager sitting side by side, with blood flowing from the kid to the oldster in a stab at anti-aging. Sort of like a one-way fountain of youth via blood flow…Sci-fi? People are kind of trying it in the real world. A self-described ‘clinical trial’ of a sort by a …

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Review of Nature paper: stem cell exosomes on the brain and aging

mouse-hypothalamus-brain-and-aging

Is there a stem cell connection between the brain and aging? Could a type of brain stem cell or the exosomes it secretes control whole body aging? A recent big Nature article from the lab of Dongcheng Cai argues an emphatic “Yes” to these questions, at least in mice. In the Zhang, et al paper, entitled …

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