Blog

Stem cells for Spinal Cord Injury update

spinal-cord-injury-MRI

The severe spinal cord injury sustained by Jockey Michael Martinez and the possibility (not realized) that he might be enrolled in Geron’s hESC-based spinal cord regenerative medicine trial, have drawn recent attention to spinal cord injury. Christopher and Dana Reeve (see foundation here) as well as Don C. Reed (see site here) were instrumental in bringing …

Stem cells for Spinal Cord Injury update Read More »

Stem Cells in Wonderland

The-White-Rabbit-from-Alice-in-Wonderland

In Lewis Carroll’s masterpiece, Alice in Wonderland, there is a wonderful passage that came to mind as I read the latest response from the self-proclaimed ‘adult stem cell researchers’ suing the government to stop federally-funded ES cell research: “I don’t know what you mean by ‘glory,’ ” Alice said. Humpty Dumpty smiled contemptuously. “Of course you …

Stem Cells in Wonderland Read More »

Keep Your Stem Cells Away From BPA

Plastic-BPA

We live in a plastic world, full of BPA. Over the last 1/2 century, the proportion of our food and beverages that are consumed out of plastic containers has skyrocketed. Unfortunately, the concentrations of plastic-related chemicals in people around the world, even in remote corners, has gone up in parallel. I’ve written about avoiding plastic …

Keep Your Stem Cells Away From BPA Read More »

Anonymous stem cell scientist frankly answers questions about the field

Anonymous-scientist-stem-cell-field

Here an anonymous stem cell scientist frankly answers questions about the field in an interview with me. Of course I have to ask you about the recent U.S. court ruling essentially declaring all federal funding of human ES cell work illegal. What’s your take on this? ANSWER: The ruling has so many flaws in it. …

Anonymous stem cell scientist frankly answers questions about the field Read More »

Grim reality of the impact of judge’s ES cell decision is emerging

Francis-Collins-ES-cell-research-lawsuit

The Obama administration has announced it will “quickly” appeal the ES cell decision, but I’m not hearing anything about a stay on the judge’s order in the meantime or anything like that. It’s quite the opposite. The NIH, in the form of Director Francis Collins, has finally spoken about the federal judge’s ruling that apparently banned …

Grim reality of the impact of judge’s ES cell decision is emerging Read More »

Parkinson’s Disease, promising new results on iPS cells

Parkinsons-Disease-stem-cells

UPDATE: A second recent study, this one in Nature Genetics has found a novel genetic link between the immune system and Parkinson’s Disease. The authors were screening for genomic variants unique to Parkinson’s patients, finding known ones but also a novel linkage. The link was with the HLA region, known to play a key role …

Parkinson’s Disease, promising new results on iPS cells Read More »

Exciting stem cell progress on Alzheimer’s Disease

Test-for-Alzheimers-Disease

UPDATE: I have added more discussion at the bottom about therapeutics and how regenerative medicine might work for Alzheimer’s Disease. Alzheimer’s Disease (AD) is the most common cause of dementia throughout the world, affecting 10s of millions of people. The cost to society is staggering and on a personal level for those of us who …

Exciting stem cell progress on Alzheimer’s Disease Read More »

Huntington’s Disease, a major new finding

Huntingtons-Disease

This is the first post in a series focusing on stem cell advances related to specific diseases. Today we discuss Huntington’s Disease and a paper that came out yesterday in the journal Neuron that provides some significant insight into the mechanisms behind the disease. It is entitled: Huntingtin Is Required for Mitotic Spindle Orientation and …

Huntington’s Disease, a major new finding Read More »

I Hate Your Paper: Dr. No and the Editors that are ruining peer review

Dr.-No-peer-review

Update: Now in 2020 it seems that peer review remains very problematic. The Scientist has a few pieces out on the trouble with peer review including my personal favorite: I Hate Your Paper. That article rings so true as do the quotes from the scientists. Peer review in the stem cell field and the IPS cell …

I Hate Your Paper: Dr. No and the Editors that are ruining peer review Read More »