August 13, 2020

The Niche

Knoepfler lab stem cell blog

CRISPR

2 min read

The International Society for Stem Cell Research (ISSCR) just now released a new policy statement on human germline gene editing. The statement calls for a ban on clinical application of human germline gene editing technology. Here is the brief summary statement at the beginning: The International Society for Stem Cell Research calls for a moratorium on attempts at clinical application of nuclear genome editing of the human germ line to enable more extensive scientific analysis of the potential risks of genome editing and broader public …Read More

6 min read

I recently interviewed leading genomics scientist George Church on the ways that trends in genomics are changing our world and the possibility of heritable human genetic modification. His answers suggest that genomics and gene editing are poised to radically change our world and to literally change us. Here’s the George Church interview you’ve all been waiting for. Do you think the public is already shifting to be more accepting of genomic information as simply another useful part of their overall health profile rather than as …Read More

3 min read

Why is CRISPR Cas9 gene editing such a big deal? Imagine being able to make mutations in any gene you wanted say in stem cells in a relatively simple, quick and affordable fashion? Sounds exciting, huh? Every so often a new kind of technology comes along in the biomedical sciences that is a true game changer. I’m talking about revolutionary technologies. Think ES cells and knockout mice, PCR, and iPS cells. Many of the biomedical scientists I know are raving about a relatively new technology …Read More