December 1, 2020

The Niche

Knoepfler lab stem cell blog

CRISPR

3 min read

Why is CRISPR Cas9 gene editing such a big deal? Imagine being able to make mutations in any gene you wanted say in stem cells in a relatively simple, quick and affordable fashion? Sounds exciting, huh? Every so often a new kind of technology comes along in the biomedical sciences that is a true game changer. I’m talking about revolutionary technologies. Think ES cells and knockout mice, PCR, and iPS cells. Many of the biomedical scientists I know are raving about a relatively new technology …Read More

1 min read

I have a poll running regarding who would have been the best choice to share the Nobel Prize with Shinya Yamanaka and John Gurdon, and so far the winner is Ian Wilmut, who cloned the first mammal, Dolly the sheep. I should have included another option to indicate the possible preference that NO ONE should have been given the honor along with Yamanaka and Gurdon. In other words, the option that the Nobel committee got it right by only giving it to two people …Read More