stem cells Archives - Page 14 of 129

Synthetic embryo or embryo model tech reported in Science: how big is this?

March 3, 2017 August 18, 2022 / By Professor Paul Knoepfler, Ph.D. / 1 Comment

Can you make a synthetic embryo, also called an embryo model? Developmental biologist Magdalena Zernicka-Goetz has long been on the trail of this seemingly almost uncatchable quarry. With her team’s publication in Science today they took a big step forward on this path even if some major hurdles remain. You can see her discussion of …

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Live blogging Future of Genome Medicine: great talks by Feng Zhang & others

March 2, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

What is the future of Genome Medicine? The meeting by that same name that I’m at down here in La Jolla is all about tackling this question and the line up of speakers today on the first day is amazing. I’m speaking about IPS cells as a basis for personalized medicine tomorrow morning so that’s exciting. …

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Navigating 4 key kinds of stem cell studies

March 1, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

Over the years and in particular after Dr. Oz’s show a couple weeks ago, I’ve heard from many patients who are absolutely convinced that stem cell therapies do in fact work and are safe. They have been focused particularly on hematopoietic stem cell therapy (HSCT) for MS but also other investigational applications using a variety of stem …

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Q&A video with Paul Episode 1: your stem cell questions answered

February 26, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 6 Comments

Where is the stem cell field now and where the heck is it heading? There are hundreds of questions. Readers often email me questions or leave them as comments. It’s not unusual to get questions about CRISPR as well. As time permits, I’m hoping once or twice a month on Sundays to post a video answering …

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Lab tour video contest: $100 prize

February 23, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

What’s your lab like? What do you work on? What are you most excited about? Is your lab hiring? What are your lab traditions? Superstitions? How messy/clean is your lab? You can see a picture of me in my lab below about 5-6 years ago…the usual busy semi-clutter of a lab. You can win $100 …

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Do stem cells for pain make any sense?

February 22, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 24 Comments

Does it make any sense scientifically or medically to use stem cells for pain? I’m skeptical in most cases today. The whole idea of stem cells for pain has been on my mind for a number of reasons. For one thing, more stem cell clinics are marketing unproven stem cell therapies at a high price …

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Kudos to Dr. Oz for stellar stem cell clinic show: time for more action

February 17, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 20 Comments

For me it’s been a wild week of grant and paper writing, grant review, going over data, and more, but finally I had a chance to watch this week’s Dr. Oz show on stem cell clinics in full last night and I give it an A+ grade. A show producer went undercover with an MS patient to a …

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Yum or yuck? Test tube bacon from stem cells

February 16, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 3 Comments

Wait…test tube bacon? Coming soonish to a BLT or breakfast near you? An article in Nature’s Scientific Reports tells us that scientists have taking some first baby steps toward bacon or at least a meaty bacon-like product from stem cells. Would you eat test tube bacon? Take our poll below. One of the possible positives of …

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Cell Surgical Network, largest group of US clinics, using lab-expanded stem cells in patients?

February 15, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 19 Comments

Is the largest affiliated group of stem cell clinics in America, Cell Surgical Network, now using laboratory-proliferated stem cells in patients? Do they already have some kind of final FDA approval for this clinical approach given that lab-grown stem cells are generally viewed as drugs requiring premarket approval? Over the years I’ve reached out to …

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National Academies panel leaves door a crack open to future human genetic modification

February 14, 2017 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 6 Comments

A National Academies panel on human genome editing chaired by Alta Charo and Richard Hynes released its report today. While it covered both somatic and germline (heritable) human genetic modification, the latter topic is far more contentious. You can see the National Academies summary of their report here. You can read the full report here. …

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