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Conservatives agree: proposed Republican budget cuts for NIH are mindless

UPDATE: Judy Woodruff just posted an interesting piece on the budget battle for NIH. You can read it here. We have had a welcome surprise of late: conservatives are telling Republicans (yes, you read that right) not to cut the NIH budget. The federal government has been running on a string of continuing resolutions (CRs) …

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Opponents of ES cell research launch stealth attack in Minnesota

Knoepfler lab stem cells

What’s going on with legislation on ES cell research in Minnesota? I blogged before about how Oklahoma legislators were heading toward passing legislation that would make it a crime to do ES cell research. Unfortunately, that legislation just passed. As if that were not bad enough, now potentially life saving research in Minnesota is starting …

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Secret Not so Secret Recipe for Safer iPS cells

IPS cells, induced pluripotent stem cells, Knoepfler lab, stained for TRA-1-60, an ES cell marker., where do stem cells come from?

Just how tumorigenic are iPS cells?  The field really doesn’t know at this point. However, a steady stream of papers have raised red flag after red flag about genomic and epigenomic alterations/mutations that are linked to cancer. Of course, then there is the fact that all the genetic changes actually used to make reprogrammed cells …

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Oklahoma leaders: ES cell research is not OK

Oklahoma-Governor-Mary-Fallin

The Oklahoma State Legislature is reportedly poised to potentially pass an outright ban of ES cell research. While in the past similar legislation was vetoed by previous Oklahoma Governor, Democrat Brad Henry, current Republican Governor Mary Fallin is likely to sign the legislation. The Oklahoman newspaper website today contains a factually incorrect, inflammatory piece by …

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The Republican “Sledge to America”

Part of the Republican’s so-called “Pledge to America” was to cut $100 billion from the federal budget. Even though fiscal year 2011 is already almost half over, Republicans driven by Tea Party Mad Hatters have proposed to cut $100 billion from the budget for this year, increasing their proposed cuts of many programs including deeper …

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Stem cell biotech updates: Geron, ACT, Neuralstem, Pfizer

What’s going on these days with biotech companies working on stem cell-based products? Geron’s and Advanced Cell Technology (ACT)’s FDA-approved trials presumably continue. As expected, no news yet. It’s too soon. Two important questions regarding both these companies are (1) did they apply for CIRM funding and (2) if so, how did the review process …

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The Inside Scoop on iPS cells early in 2011

It’s been more than 4 years since Shinya Yamanaka published the remarkable finding that his lab could transform or “reprogram” regular cells called fibroblasts into a very unique state that was quite similar to that of embryonic stem cells (ESC).  Yamanaka called these new cells “iPS cells” for induced pluripotent stem cells. Since that time, …

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Science is a national security issue

Reportedly,  House Republicans are proposing a continuing resolution (CR) to fund the rest of FY2011 at 2008 funding levels.  To achieve such an end, the Republicans would have to invoke serious cuts through the federal budget. Not only would such cuts likely damage the U.S. economy, but also they would have major other negative consequences. …

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