Search Results for: mscs

My take on the much-touted ‘SafeCell’ paper on adult stem cell safety: encouraging, but some important reservations

The so-called “SafeCell” paper from the journal PLoS One is one that a number of advocates of deregulation of the stem cell industry often have mentioned to me: Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials  I have read this paper and have some thoughts on it. As …

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Would an MSC by any other name still smell as sweet?

The mesenchymal stem cell (MSC). So important and yet so misunderstood? People pronounce it in different ways. People isolate the MSCs in different ways. Each person’s MSCs are very different. Each lab’s MSCs are different. (see picture above of MSCs showing fibroblastic morphology; source is Wikipedia) Someone once told me that MSCs are the same …

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Some 2012 papers that raise serious safety concerns about adult stem cell treatments

Just how safe are stem cell transplants? Is an autologous stem cell transplant always safe? Is it really true, as one stem cell transplant doc once said of autologous stem cell treatments, that “the worst thing that could happen is the treatment won’t work”? Are adult stem cell treatments by definition safe? The reality is …

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Critically reading science papers: response to patient on MS stem cell literature

One of the most important elements of science is critical reading of papers. Most of us come into science as undergrads feeling somewhat naive about what we read in papers. Our default tendency is to believe most or all that we read as “true”. As we get more experienced, we realize that in fact if …

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Interview with NeoStem CEO Robin Smith Part 2: VSEL, ES cells, and iPS cells

I recently did a Q&A interview with NeoStem CEO Dr. Robin Smith. I posted Part 1 of that interview a few days ago here. Now we have part two focused on VSEL, ES cells, and iPS cells. PK: I frequently have readers of my blog ask questions about VSEL. They seem puzzled and unsure of …

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Eight simple reasons not to get an unlicensed stem cell treatment: #4, undesired tissue growth (e.g. bone in your eye)

So far in my series of eight simple reasons not to get an unlicensed stem cell treatment I’ve covered three compelling reasons: potential loss of insurance coverage for negative outcomes that could cost hundreds of thousands of dollars, failure of patient follow up by the doctors and clinics, and exclusion from future clinical trial participation. …

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Mapping global trends in MSC & stem cell clinical trials: unexpected findings

One of the most exciting types of stem cells are mesenchymal stem cells or MSCs. Although there is some debate about these cells (e.g. I once heard Irv Weissman say at a meeting he wasn’t sure they really existed as such), a consensus would seem to be that they have great potential medical potential. Perhaps …

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Intriguing interview with Robin Young, Organizer of Houston Stem Cell Summit

Next month will be the 1st Houston Stem Cell Summit organized by Robin Young, who also organizes the New York Stem Cell Summit. I’ve been a bit tough on this meeting for a perceived lack of diversity in their program of speakers. I interviewed Robin Young (RY) about the meeting and found his answers quite interesting …

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