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Stem cell news bites: microbiota, clinic doc death, Stem Cells Inc, & more

gut-stem-cells-microbiota

This edition of our stem cell news bites finds a number of notable stem cell news items. A potentially cool link between gut stem cells and microbiota is reported by Tae-Hee Kim of the Ontario Institute for Regenerative Medicine. See the nifty image of the stem cells from Dr. Kim showing proliferating gut cells in …

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ISSCR Releases Flood of Stem Cell Policy Docs

ISSCR-Policy-Guidelines-2016

A committee of the International Society for Stem Cell Research (ISSCR) did one heck of a document dump yesterday on stem cell policy, releasing a whole bunch of policy recommendations on stem cells and more. The torrent from ISSCR included a 37-page policy statement itself as well as several papers in top journals including the …

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Perspectives on Vatican Stem Cell Meeting: CIRM, Embryonic & Adult Stem Cells

Vatican-stem-cell-meeting

Over the years, the Vatican has expressed interest and even invested money in the adult stem cell field. Not surprisingly, they’ve also been critical of embryonic stem cell research. Interestingly their own stem cell meetings have at times stimulated heated debate for various reasons and one was even cancelled with at least part of the reason related to …

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Live Blogging #GeneEditSummit Day 1 Post #3: human germline modification

Robin-Lovell-Badge-Peter-Braude-George-Church

The post-lunch session is “Applications of Gene Editing Technology: Human Germline Modification”. Prior to hearing it I’m curious how cautious or gung-ho the speakers will be, or if their gestalt will be one of balance in the middle somewhere. Robin Lovell-Badge, The Francis Crick Institute, was the moderator of this session. He said, “We’d be …

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Key Remaining Questions about STAP Cell Mess

STAP-stem-cells-hope-or-mirage-201x3001

The publication yesterday of two papers refuting the existence of so-called STAP cells marches us closer as a field toward closure on this unfortunate situation. Close, but not quite there. We know a lot more about what went happened, but 5 key questions remain. There is a chance that we may never get answers to …

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New Nature papers debunk STAP cells

STAP-refutation

Today marks nearing the completion of a full circle for one of science’s biggest controversies: the STAP cell fiasco. Today STAP cells are completely refuted with the publication of two new papers in Nature and we know much more–with some notable gaps still–about what went wrong. STAP cells debunked In January of last year, an …

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NAS Meeting on Human Germline Modification Taking Shape

NAS-CRISPR3

The US National Academy of Sciences (NAS) will hold a meeting on heritable human germline modification on December 1-3, 2015 in Washington, D.C. Invitations to the NAS meeting to individuals starting going out last week. The upcoming NAS meeting seeks to address these issues and discuss the possibility of a moratorium on clinical use of …

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Researchers in China make genetically modified human embryos

Liang-P.-et-al.

Rumors have been flying for months that researchers in China and possibly elsewhere were shopping papers around at high-profile journals that reported gene editing and genetic modification of human embryos. Update: apparently this paper (HT to @JohnBorghi) was only reviewed for 2 days (see image at bottom of post), raising major concerns about the depth of …

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David Baltimore, et al. path for human germline engineering

human-germline-editing-policy

In a new perspectives piece in Science, Nobel Laureate David Baltimore and co-authors including Jennifer Doudna and George Church, chart a potential path forward for human germline engineering. See also accompanying Bioethics piece by Gretchen Vogel as well, “Embryo engineering alarm”. In the piece, entitled “A prudent path forward for genomic engineering and germline gene …

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