Search Results for: jun takahashi

Hope on Parkinson’s front: Japan IPSC trial 1st patient

Fig-3i-Kikuchi-et-al.-Nature-2017-IPS-cell-Parkinsons-

In Parkinson’s Disease patients develop neurological dysfunction as they lose a special kind of brain cell called dopaminergic (or dopamine) neurons. While a number of different approaches to this disease have been studied for decades, nothing has proven particularly successful in slowing its progression. As a result there has been a big need for novel thinking …

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Ian Wilmut, who cloned Dolly, opens up about his Parkinson’s Disease

Ian-Wilmut

One of the most famous living biological scientists, Sir Ian Wilmut, just announced that he has Parkinson’s Disease. I wish him the best in dealing with this illness. Wilmut is very well-known for having cloned the first mammal, Dolly the Sheep. This work followed on the earlier breakthrough by Sir John Gurdon of cloning the …

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20 Stem Cell Person of The Year 2017 Award Nominees

stem-cell-person-of-the-year

Nominations have closed for the 2017 Stem Cell Person of the Year Award and we have a great group of nominees. I’ve listed them below in alphabetical order, along with a bit of description of who they are, which includes in some cases the language used by the nominator(s). Where possible I’ve included a link …

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On the threshold of cell therapy for Parkinson’s disease

Dopamine-neurons-derived-from-a-Parkinsons-disease-patients-iPSCs-Tyrosine-hydroxylase-1

By Jeanne Loring There are ten million people in the world who have Parkinson’s disease. 125,000 of these are living in California.  People with the disease often have to step away from their jobs because the main symptoms – tremor or freezing up of muscles – make it difficult to get through a whole day …

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20 Nominees for Stem Cell Person of the Year 2016 Award

Stem-cell-person-of-the-year-award

I received a score of great nominations for the Stem Cell Person of the Year 2016 Award and have briefly described the twenty nominees below. The point of the award is to honor the top positive stem cell leader who specifically thinks outside the box and takes risks. I’ve started an on-line vote where you can vote once per day for …

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Parkinson’s IPS cell trial in Japan switching to allogeneic

Jun-Takahashi

What’s better for stem cell trials such as for vision loss or Parkinson’s Disease: allogeneic or autologous cells? In a major shift earlier this year, the induced pluripotent stem (IPS) cell trial in Japan for treatment of macular degeneration (MD) switched gears from using the patients’ own cells (called “autologous”) to using banked cells from …

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Michael Cea ISSCR chat with Jeanne Loring on stem cell field

Lewy_Body_alphaSynuclein

ISSCR Chat By Michael Cea Jeanne Loring of the Scripps Research Institute in La Jolla, California kindly sat down with me at the ISSCR annual meeting for a broad discussion of her history, views on the field and developments in the science. I found Jeanne a refreshing character, as I did a number of others I was …

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Overview of Yamanaka Talk at #ISSCR2015 by Heather Main

Heather_Main

The day of plenary is the most enjoyable in my view including at ISSCR 2015 on the first day with a Yamanaka talk. You don’t need to make the choice between sessions and the judgement on the viability of shifting sessions versus staying put and listening to the slightly less relevant. ISSCR 2015 plenary was, …

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Shinya Yamanaka Interview on Clinical Use of IPSC

Dr.-ShinyaYamanaka

I invited Nobel Laureate Shinya Yamanaka to do an interview on the future of clinical translation of induced pluripotent stem cells (iPSC). He provides some intriguing new insights into the iPSC field and the broader stem cell arena. PK: The Takahashi Team’s active Clinical Study using iPSCs to make RPEs to treat Macular Degeneration has …

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Trial of Stem Cells for Parkinson’s Disease on Horizon

Is a treatment based on stem cells for Parkinson’s Disease on the horizon? A Japanese team of researchers led by Dr. Jun Takahashi, professor at Kyoto University is reportedly aiming to start on human studies of an induced pluripotent stem (iPS) cell-based treatment for Parkinson’s Disease (PD) as early as fiscal year (FY) 2014. In …

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