Search Results for: us stem cell

Mitalipov Nature pub review: IPSC & SCNT for mitochondrial disease

February 1, 2021 / By / 6 Comments
Mitalipov-IPSC-paper

In a new, thought-provoking paper today in Nature, Shoukhrat Mitalipov and a multi-institutional team report a significant advance toward potential novel ways to treat mitochondrial diseases. What are these illnesses? Mitochondrial diseases are rare, but devastating disorders caused by genetic mutations. Today they are largely impossible to treat in meaningful ways other than palliative care. Some …

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Masayo Takahashi (高橋 政代) on IPSC Trial for Vision

December 22, 2023 / By / 9 Comments
Monkey-stem-cell-RPEs

Masayo Takahashi (高橋 政代) on IPSC Trial for Macular Degeneration By Michael Cea Stem Cell Analyst & Advocate (editor’s note: piece was originally posted on Michael’s blog here; follow Michael on Twitter @msemporda) Masayo Takahashi interview Having followed closely the developments in programs using pluripotent based therapeutics I was fortunate during ISSCR2015 to have the opportunity to …

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Interview with transhumanism leader Maria Konovalenko

February 1, 2021 / By / 21 Comments
Maria-Konovalenko

The transhumanism movement has been garnering attention lately for a variety of views including embracing aspects of heritable human genetic modification. Earlier this year I interviewed geneticist and transhumanist, George Church. In this post I interview molecular biophysicist and transhumanist Maria Konovalenko. She is the program coordinator at the Science for Life Extension Foundation. In …

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Landmark IPSC clinical study on hold due to genomic issue

December 22, 2023 / By / 42 Comments
IPSC-RPE-sheet

The pioneering induced pluripotent stem cell (IPSC) clinical study in Japan led by top stem cell clinical researcher Dr. Masayo Takahashi has been stopped reports the WSJ in Japan. This development is confirmed by other sources and in a PDF report by RIKEN (in Japanese here). One patient was transplanted in September 2014 with their own IPSC-derived …

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Carla Kim & Hans Clevers talks on organoids at #ISSCR2015

February 1, 2021 / By / 4 Comments
liver-organoid

Organoids are pretty big in stem cells right now with the last couple of years having attracted a lot of media attention on mini lungs, mini brains, mini kidneys, mini guts and more, giving the impression that scientists know how to specify and organise cells into mini functional organs in the lab. Organoids have become …

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Overview of Yamanaka Talk at #ISSCR2015 by Heather Main

February 1, 2021 / By / 1 Comment
Heather_Main

The day of plenary is the most enjoyable in my view including at ISSCR 2015 on the first day with a Yamanaka talk. You don’t need to make the choice between sessions and the judgement on the viability of shifting sessions versus staying put and listening to the slightly less relevant. ISSCR 2015 plenary was, …

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Sally Temple on adult RPEs for vision impairment, IND, & more

December 22, 2023 / By / 4 Comments
Sally-Temple-cells

At the recent RPI stem cell and bioengineering meeting, the Neural Stem Cell Institute’s Sally Temple talked about her group’s intriguing retinal pigmented epithelial cell (RPE) research. With the broad focus of attention in the world of RPEs mostly on those derived from either human ESC or IPSC, it was exciting to here about the …

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Will bioengineered body parts cost an arm and a leg?

February 1, 2021 / By / 3 Comments
deka-arm1

The idea that we could bioengineer new human body parts to replace old, faulty ones is exciting, and such parts could include limbs, digits, or even entire organs. Such replacements might be produced using stem cells, 3-D printers, and other rapidly evolving, cutting edge technologies. Sci-fi is becoming a reality. Remember in Star Wars when …

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Americans relatively more comfortable with human cloning

February 1, 2021 / By / 1 Comment
Gallup-cloning

What is morally acceptable and where do we draw the line at behaviors that might just go too far such as human reproductive cloning? Over the years American attitudes have shifted on a number of potentially hot button moral behaviors including reproductive human cloning and pollsters including Gallup have tracked these attitudes. Gallup just came out …

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