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Readers across the globe favor moratorium on gene editing of human germ cells in poll

March 18, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

In a still ongoing on-line poll, readers of this blog show a pattern of consistently favoring a moratorium on genetic modification of human germ cells. With more than 150 votes cast, the top two answers are ‘strongly favor’ and ‘favor’ a moratorium on human germline genetic modification. Only 15% strongly opposed a moratorium. Overall those …

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Monday, March 2: My Reddit AMA on 3-Person IVF – Mitochondrial Transfer

February 27, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

On Monday, I’ll be doing another Reddit AMA, this time on 3-person IVF also known as 3-parent IVF, mitochondrial transfer, 3-parent babies, etc. You can see the upcoming AMAs including mine listed in the right sidebar here. Mine will start at 10AM PST/1PM EST. I hope to discuss with a wide audience all the key …

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Myths about 3-person IVF mitochondrial transfer

February 10, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 11 Comments

It’s been somewhat of a helter-skelter time for the new technology often referred to as 3-person IVF or mitochondrial transfer as the UK considers whether to legalize this experimental technology for use in humans. I believe that this technology is not ready now for use in humans and for more background on why as well …

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Reflecting on the wild week that was

February 8, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 2 Comments

This was a crazy week for me. I’m mostly taking today off, meaning “only” working a few hours on a Sunday. I submitted an R01 application on Tuesday. This is a huge grant application that is a major undertaking to write and put together. Getting it out the door this week was a big relief. Fingers …

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Human GMO Method Given OK by UK Parliament in Historic Vote

February 3, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

The UK Parliament just voted to legalize the production of genetically modified human beings. To my knowledge, this is the first time in history that such a vote has given the green light to make GMO human beings in any country of the world. There are other hurdles before this method can actually be used including the …

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Stem Cell Predictions for 2015

December 28, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 3 Comments

Every year I do a list of top predictions for the coming year for the stem cell and regenerative medicine field. For example, you can see past top 10 predictions lists for 2013 and 2014. What’s in store for 2015 from the stem cell crystal ball? There is so much going on that for this …

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Dieter Egli Interview: NT-ES cells, IPSC, Mitochondrial Transfer, & More

November 17, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 3 Comments

It’s a particularly exciting time for the stem cell field. One of the most notable developments in the last year or so is the production and preliminary study of a totally new type of human embryonic stem cells (ESC) made by nuclear transfer instead of using leftover in vitro fertilization (IVF) embryos. This process of so-called …

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Open letter to UK Parliament: avoid historic mistake on rushing human genetic modification

November 2, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 1 Comment

Dear UK Parliament and Science and Technology Committee, I am writing to you about your deliberations on “mitochondrial donation” (also known as 3-parent technology) intended for the purpose of preventing heritable mitochondrial disorders. I am concerned about the Department of Health’s recent draft regulations that would allow 3-parent experiments to go forward and the possibility that the UK …

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