Search Results for: embryonic stem cell

Do human Very Small Embryonic-Like Stem Cells (VSEL) exist as a normal population of actual stem cells?

Supposedly there is a type of normal adult stem cell that intrinsically possesses many of the same properties as embryonic stem cells (ESCs). No reprogramming needed. No blastocysts needed. These reportedly amazing cells, called Very Small Embryonic-Like Stem Cells (VSELs), can in theory be isolated from umbilical cord blood (UCB) or even bone marrow. Yet …

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ViaCyte purchase puts Vertex in driver’s seat on stem cells for diabetes

Doug Melton, Vertex, ViaCyte

When I’m asked about the most promising areas of stem cell clinical research, cell therapy for type I diabetes is near the top including work by a biotech called ViaCyte. Other firms are in the mix too, boosting the overall odds of success in the coming decade. It’s really that promising even though there are …

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Weekly reads: freeze-dried cloning, FDA signals, stem cell escapees

Human-cloning

Cloning is one of those topics that both fascinates and kind of scares people, especially the idea of duplicating people. I regularly cover the topic here on The Niche because stem cell technologies are involved. Also, one form of the process sometimes called “therapeutic cloning” involves embryonic stem cells. Duplicating mammals has now long been …

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Fact-checking VSEL stem cells & supposed ‘VSEL treatment’

VSELs, vsel ratajczak paper issues

A few people in the stem cell field keep arguing that adult pluripotent stem cells exist, including so-called “very small embryonic-like stem cells” or VSEL stem cells. These days the supposed cells are called VSELs or V-cells too. Only a handful of researchers have ever been able to report finding and studying these cells. Others …

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Weekly reads: neural stem cells, CRISPR brain, Vertex, cytoplasm surprise

neural stem cells

Some people consider the brain to be equivalent to a living computer and in that sense it’s too bad that computers don’t have the equal of neural stem cells to help them fix themselves. Is the internet one big neural network-like web? There was a quake in the stem cell internet as CIRM’s main website …

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Weekly reads: Melton leaves Harvard, Fuji, BBC blunder, stem cell niche, more

Senolytics restore the stem cell niche in the brains of mice. Fatt, et al. Stem Cell Reports 2022.

Sometimes a post here on The Niche (named after the stem cell niche) sparks a debate between expert stem cell researchers and often that gives much more depth to a topic. Such was the case with my post this week on where things stand with stem cell therapy for heart disease. It led to a …

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Stem cell weekly reads: Jamie Thomson, Lamin B1, CRISPR

james-a.-thomson-214x3001

The big news of the week was a $3.6 million settlement by a stem cell clinic, StemGenex, and one of its doctors in a class-action suit. I covered this StemGenex settlement and so did Michael Hiltzik of the LA Times and Paul Schloesser at Endpoints. I’d say this was good news for the stem cell field …

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Weekly reads: possible rare HIV cure, stem cell chicken, FDA commish

HIV infected T cell, HIV cure

The idea of stem cells outright curing diseases is exciting and has powerful appeal, but media need to be careful about using the word cure in headlines and articles as we saw this week related to a possible HIV Cure. HIV cure via stem cells and chemo? The big news of the week was that …

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Recommended reads: senolytics, cow iPS cells, big CIRM royalty

Senolytics Steve Horvath

When we hear the word senile we might think stereotypically of an older person who has cognitive impairment, but some argue that senility can apply to cells too as they age and that such cells can be targeted by drugs called senolytics. Unfortunately, the supplements industry has picked up on this idea to sell iffy …

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Recommended reads: stem cell scientists, eggs from blood, Cryo-Cell

Nobel Laureate Shinya Yamanaka, the first to produce induced pluripotent stem cells

We’ll begin this week’s recommended reads with some news on two wonderful stem cell scientists. While there are thousands of stem cell scientists, some stand out for their especially creative work. News on stem cell scientists   Nobel laureate Yamanaka to retire as director of iPS cell center, Asahi Shimbun. Dr. Yamanaka will spend more time …

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