Search Results for: myc

Weekly stem cell reads: Google Bard AI issues, fat ball reprogramming, BrainStorm on ALS

July 29, 2023 / By / Leave a Comment
stem cell research

It’s great finding stem cell videos on YouTube that are either excellent research talks or provide important information. I recently found one such video by Shiri Gur-Cohen, which I included below. Interesting data there and Shiri is such a compelling speaker. She also won The Niche image contest one year with a cool microscopy pic …

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Review of new David Sinclair paper, supplements & anti-aging glitz

August 2, 2023 / By / 7 Comments
David sinclair, anti-aging

Who is David Sinclair and why is he all over the media related to anti-aging efforts? This post is my effort to fact-check Sinclair’s statements in the context of the broader rejuvenation arena. In the process I also review his most recent paper from my view as a stem cell and cancer biologist interested in …

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Weekly reads: reprogramming hearing loss, heart disease, eye drops, sickle cell

April 29, 2023 / By / Leave a Comment
Regener-Eyes, eye drops

It’s mostly been a week of good and encouraging news in the regenerative medicine space including with gene therapies maybe with the exception of some eye drops warning (more below). There’s realistic hope for an approved sickle cell disease soon. I also see some long-term positive news on hearing loss research. Hematopoietic stem cell transplant …

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Perspectives on David Sinclair anti-aging Cell pub & in vivo reprogramming

February 9, 2023 / By / 2 Comments
methuselah mouse, anti-aging

About twenty years ago a science story made big news of a so-called anti-aging Methuselah gene. Methuselah gene and anti-aging The claim was that this DNA conferred long life on people. Hence the name Methuselah, which refers to a man from the Bible who reportedly lived 969 years. The so-called Methuselah gene was at first not a …

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Weekly reads: Kevin McCormack passes, HSCs & RXR, Ethics

December 17, 2022 / By / 3 Comments
Kevin McCormack, Paul Knoepfler, stem cell research

Out of the blue this past week we lost Kevin McCormack of CIRM to a heart attack. When I first heard, my reaction was that can’t be, but it is. About Kevin McCormack If you aren’t familiar with him, Kevin was officially Director of Patient Advocacy at our state’s Stem Cell Agency. However, he was …

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Weekly reads: Marc Tessier-Lavigne probe, Neuralink on the brain, Ras unchained

December 3, 2022 / By / Leave a Comment
Marc Tessier-Lavigne

We’ll start with a story related to possible research misconduct, Stanford’s President Marc Tessier-Lavigne, and Science Magazine.  In some ways the news on Science itself could be the bigger long-term story. Marc Tessier-Lavigne pub investigation, Science oops moment Here’s some of the coverage: Stanford investigates potential misconduct in president’s research, Science. Multiple publications of Marc Tessier-Lavigne …

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Weekly reads: NurOwn, key gene screen, MS, Croce mess

November 13, 2022 / By / 3 Comments
Nurown BrainStorm

I get a lot of questions about stem cells for ALS and more recently people have been specifically interested in NurOwn from BrainStorm Cell Therapeutics. Recently, the FDA denied BrainStorm’s request for a BLA for NurOwn. The company felt its Phase III trial was encouraging. It sounds like they will move forward with a follow-up …

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Weekly reads: KRAS G12C, eLife journal controversy, bird iPSCs

October 29, 2022 / By / 2 Comments
KRAS mutations, KRAS G12C

If you’ve never heard of the KRAS G12C mutation, it’s a particularly frightening mutation present in numerous cancers. Like the MYC oncogene, many people view mutations in RAS as undruggable, but new efforts show some glimmers of hope. The drug Sotorasib has been approved by the FDA to target the KRAS G12C mutation. Here’s a …

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Histone code series: H3K27me3 & H3K27ac functions & roles in diseases like DIPG

August 9, 2022 / By / 1 Comment
ASCL1 in K27M tumors, H3K27me3 loss

Histone proteins such as histone H3 are often popping up in science writing and news sometimes includes specific modified forms of H3 including one that we scientists call H3K27me3. What is in this article What is H3K27me3? | The histone code | H3K27ac and H3K27me3 function | H3K27 and human disease | References The goal of today’s post …

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Stem cells for MS & other weekly reads: CRISPR, COVID & a bat cave, Huntington’s

March 5, 2022 / By / 1 Comment
Symptoms_of_multiple_sclerosis.svg_

About 1 million people are living with multiple sclerosis in the U.S. alone with millions of other cases around the world so a huge effort has gone into trying to find new approaches to the disease including stem cells for MS. We’ll start our weekly recommended reads by talking about a new paper on MS …

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