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Weekly reads: grad student life, cell barcoding, diabetes trial, more

ViaCyte capsule stem cells diabetes

Part of being a grad student is dealing with technologies related to your projects and their limitations. Sometimes I feel old when I remember the way we used to have to do things in the lab. As a grad student, I manually poured, ran, and read giant sequencing gels. Back then, gene synthesis of a …

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Regenerative reads: 3 CRISPR babies, FDA warning, diabetes, pubs

CRISPR-baby

If you celebrate the Thanksgiving holiday I hope you had a nice one and, right before it started a new article popped on the scene about the CRISPR babies. Before we discuss those three gene-edited people, who are now growing up into little kids, we hit a milestone on our YouTube Stem Cell Channel with …

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Startup Clade from CRISPR Therapeutics founder pursues cloaked stem cells for cancer therapy

Chad-Cowan CRISPR Therapeutics

CRISPR Therapeutics has been pursuing the idea of using gene-editing to make universally compatible stem cells for some time, but there’s an new development in this space. The potential here is big. What if you could make cloaked stem cells that could be used to produce cellular therapies that could be given to most patients …

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Vertex upbeat on 1st stem cell therapy for diabetes trial participant

“While still early, these results support the continued progression of our VX-880 clinical studies, as well as future studies using our encapsulated islet cells, which hold the potential to be used without the need for immunosuppression,” said Bastiano Sanna, Ph.D., executive vice president and chief of cell and genetic therapies at Vertex.

It’s hard in the cell therapy field not to get excited even with bits of seemingly encouraging news but with N=1 reports we have to be very cautious and that’s the case with news from Vertex on their 1st stem cell therapy for diabetes trial participant. Vertex stem cell therapy for diabetes VX-880: N=1 This …

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Stem cell therapy for diabetes updates: expected IPO, CRISPR, new pubs, more

stem cell therapy for diabetes

The idea of stem cell therapy for diabetes is both exciting and in a way practical. By that I mean that there’s a good common sense foundation here. The idea of stem cell therapy for diabetes What do I mean? If medical researchers can replace lost beta cells in the pancreas using stem cell-produced beta …

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What are embryonic stem cells & where do they come from?

Knoepfler lab stem cells

What are embryonic stem cells and how are they obtained? My lab has been doing research on embryonic stem cells for more than 14 years. You’ve come to the right place for expert answers on these very intriguing cells. What’s in this article Where do embryonic stem cells come from? | SCNT or cloning stem cells …

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24 cell therapy & stem cell stocks I’m following

stem cell stocks

Stem cell stocks, meaning cellular therapy biotech companies, face many challenges, but their clinical research is crucial. Stem cell biotechs These biotechs have ups and downs, sometimes at the same time. This is kind of the standard of “life” as any biotech company. It is definitely the case in the volatile stem cell and cell …

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Grading my 20 stem cell predictions for 2020

Knoepfler-The-Niche-stem-cell-blog-predictions-2020

Each year I metaphorically try to look into a crystal ball for stem cell predictions for the coming year and I did so for 2020, but the COVID-19 pandemic threw a monkey wrench into my predictions. It actually kind of blew some up. It also raised some interesting questions and dilemmas. For instance, do many …

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Stem cell reads: IPS cells, p53, mini-livers, baldness

stem-cell-grown-mini-liver-small

We’ve had another week of interesting stem cell news and papers. Here is an aggregate of the stem cell and regenerative medicine week that was. Stem cell therapy for baldness I’ve covered stem cells for hair loss for about a decade here on The Niche. While it seems like it’s taken a long time for …

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20/20 vision? The Niche’s 20 stem cell & regenerative medicine predictions for 2020

The-Niche-stem-cell-predictions-2020

Every year in December and early January I do a post predicting some key events for the stem cell and regenerative medicine field for the upcoming year and today’s post contains my predictions for 2020. You can see my past 2019 predictions along with my grades for them here. I gave myself a B+ for …

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