Search Results for: organoids

Weekly reads: stem cell videos, cystic fibrosis, papers

stem cell videos

As part of our weekly reads I’m including one of my latest videos in our Stem Cell Channel on YouTube below. This particular video fact-checks stem cell face creams, but I’ve got quite a few more including on stem cell supplements, different kinds of stem cells and more. You might guess my view of such …

Weekly reads: stem cell videos, cystic fibrosis, papers Read More »

Fact check: Lung Health Institute & cell therapies for lung disease

the lung health institute

What should we make of clinics like the Lung Health Institute? These clinics sell unproven stem cell or regenerative therapies for lung disease. Overall, I’m extremely skeptical. I don’t believe it’s worth the cost. There are also going to be potentially serious health risks. Lung disease is a broad category including COPD, emphysema, pulmonary fibrosis, …

Fact check: Lung Health Institute & cell therapies for lung disease Read More »

Hub of Regenerative Medicine & Stem Cell Meetings 2021

stem cell meetings 2021

Science must go on and so must stem cell meetings 2021 with all those great conferences out there, but this year it’s going to be different, right? Every year I put up a continually-updated list of stem cell meetings and conferences. I’ve got my 2021 even if most of what’s out there is going to …

Hub of Regenerative Medicine & Stem Cell Meetings 2021 Read More »

Recommended reads: jobs, FDA letter, & The Niche new look

the body building fda letter the niche

During the week as I’m doing other stuff I keep my eyes open for interesting things to read, including over the weekend about stem cell research, COVID, CRISPR, and more for The Niche weekly recommended reads. This week a lot was going as we updated The Niche site to our new theme and format. I …

Recommended reads: jobs, FDA letter, & The Niche new look Read More »

What are induced pluripotent stem cells or IPS cells?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or iPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too. This may manifest both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as …

What are induced pluripotent stem cells or IPS cells? Read More »

Grading my 20 stem cell predictions for 2020

Knoepfler-The-Niche-stem-cell-blog-predictions-2020

Each year I metaphorically try to look into a crystal ball for stem cell predictions for the coming year and I did so for 2020, but the COVID-19 pandemic threw a monkey wrench into my predictions. It actually kind of blew some up. It also raised some interesting questions and dilemmas. For instance, do many …

Grading my 20 stem cell predictions for 2020 Read More »

What are totipotent stem cells & what can they do?

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Sometimes patients or my students ask me, “What are the best stem cells?” what information are they looking for? I think they often are looking for the most powerful stem cells so perhaps they should be asking, “What are totipotent stem cells?” Other times it seems what patients specifically want to know is what might …

What are totipotent stem cells & what can they do? Read More »

Overview of IPS cell prospects for clinical impact

IPS-cell-clincial-trials-map

IPS cell research is a growing area of promise for regenerative medicine. These stem cells, also known as iPSCs or more formally as Induced Pluripotent Stem Cells, are engineered cells that are programmed to function the same way as embryonic stem cells. They can be differentiated into possibly any type of cell that is needed for …

Overview of IPS cell prospects for clinical impact Read More »

Can Gene-Edited Stem Cells Treat Cystic Fibrosis?

human-IPS-cells-made-in-Knoeplfer-lab-stained-for-TRA-160

Drugs that restore the shape of the errant protein behind cystic fibrosis (CF) have, over the past eight years, helped the majority of patients, who have certain mutations. Gene-corrected stem cells might offer a “mutation agnostic” option to CF. CF results from a glitch in a glycoprotein with the unwieldy name “cystic fibrosis transmembrane conductance …

Can Gene-Edited Stem Cells Treat Cystic Fibrosis? Read More »

Weekly reads: lab meat, crow brain biology, direct reprogramming, more

Stacho-et-al-Science-2020-Fig-1small

Does time seem somewhat warped to anyone else in 2020 even without having  had COVID, which could alter brain function? It just seems like with everything going on that time simultaneously both drags and zooms by this year. One sort of reassuring element is that papers keep on being published so we can enjoy cool …

Weekly reads: lab meat, crow brain biology, direct reprogramming, more Read More »