Search Results for: stem cells anti-aging

Weekly reads: oocytes from males, David Sinclair longevity inc, diabetes, He Jiankui

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David Sinclair

A team led by Harvard professor David Sinclair had a recent Cell paper on reprogramming to fight aging that I reviewed here on The Niche. I thought the paper was exciting and important. Note that in vivo reprogramming was first done more than a decade ago. Sinclair did have a novel fast-forward aging method and overall […]

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Weekly reads: reprogramming aging, astrocytes, cartilage, ChatGPT

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Let’s start with a couple of new pieces on in vivo reprogramming. The idea here is to do something like making iPS cells but doing it inside organisms and not quite pushing cells all the way back to pluripotency. Just younger, healthier cells. Why do that? The goal is to achieve a kind of anti-aging

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Fact-checking exosome therapy: costs, risks, & lack of data

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model of an exosome, exosome therapy

Exosome therapy is a still-experimental cell therapy approach aimed at treating specific diseases using secretions from cells. It’s novel since most attention on cell therapies has been given to using the actual cells themselves. In addition, this approach is a newer idea than using cells as the drug to treat diseases. Interestingly, the term “cell

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Nature paper claims young CSF fights brain aging in mice

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old mice get young CSF

A new Nature paper argues that young CSF fights brain aging. Young CSF vs. young blood CSF is the cerebrospinal fluid that surrounds the brain, including those of young mice. The claim is that when young CSF is injected into the brain/CNS cavity of old mice, it makes the aged brains seem younger. And function

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All about Altos Labs & its $3B cellular rejuvenation push

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Altos Labs PIs

I wrote briefly a few months ago about Altos Labs. It’s a new kind of biotech institute that is focused on cellular reprogramming. Now we know much more and it’s clear this is a huge deal. What’s in this article What is Altos Labs? | Cellular rejuvenation | Reprogramming oldness | Challenges | Altos Strategies | Analysis of

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Unnatural Selection review: captivating mind-bender but needed more science

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Unnatural-Selection-with-patient-Jackson-Kennedy

Today’s post is a review of Unnatural Selection, the new Netflix science docuseries focused on CRISPR and other disruptive genetic and reproductive technologies. The show is an interesting mix of personalities and stories from patients, scientists, biohackers, and more. One patient thread is the story of a wonderful little boy named Jackson Kennedy. He wants

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Interview with transhumanism leader Maria Konovalenko

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Maria-Konovalenko

The transhumanism movement has been garnering attention lately for a variety of views including embracing aspects of heritable human genetic modification. Earlier this year I interviewed geneticist and transhumanist, George Church. In this post I interview molecular biophysicist and transhumanist Maria Konovalenko. She is the program coordinator at the Science for Life Extension Foundation. In

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Post-Publication Paper Reviews & Commentaries

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2015 Review of Vogelstein “Bad Luck” Cancer & Stem Cell Paper in Science January 02, 2015   2014 What Does New Paper Mean for Future of Nuclear Transfer ES Cells? November 9, 2014 Encouraging New Paper on ACT Stem Cell-Based Trial for Macular Degeneration October 14, 2014 Top 10 Takeaways From Harvard Stem Cell Diabetes

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L’Oreal Lancome gets hammered by FDA, why kid gloves for clinics?

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Patricia-Pineau-300x2541

Stem cell cosmetics is an exploding area ranging from facial creams (e.g. from L’Oreal and its Lancome) to face lifts to boob jobs to baldness treatments (see two key posts here and here for background and great stories). The stem cell cosmetics field has not been held back by issues such as the fact that

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