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Interview with transhumanism leader Maria Konovalenko

July 6, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 21 Comments

The transhumanism movement has been garnering attention lately for a variety of views including embracing aspects of heritable human genetic modification. Earlier this year I interviewed geneticist and transhumanist, George Church. In this post I interview molecular biophysicist and transhumanist Maria Konovalenko. She is the program coordinator at the Science for Life Extension Foundation. In …

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Sexism in Science and Tim Hunt

July 2, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 8 Comments

Sexism in science is a very real, big problem, and the Tim Hunt situation is just one example. For a reality check on that particular train wreck and background see this piece by Connie St Louis. The sexism prevalent in science not only has negatively affected tens of thousands of scientists, but also is quite …

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Landmark IPSC clinical study on hold due to genomic issue

July 1, 2015 December 22, 2023 / By Professor Paul Knoepfler, Ph.D. / 42 Comments

The pioneering induced pluripotent stem cell (IPSC) clinical study in Japan led by top stem cell clinical researcher Dr. Masayo Takahashi has been stopped reports the WSJ in Japan. This development is confirmed by other sources and in a PDF report by RIKEN (in Japanese here). One patient was transplanted in September 2014 with their own IPSC-derived …

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Monday morning musings: stocks, ISSCR, grants, CRISPR, New Book

June 29, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

What’s on your mind on this Monday morning and are you caffeinated enough yet? Depending on where you live it may even be time for dinner, bed, or already early Tuesday. Here are some Monday musings… To get safe and effective stem cell treatments to patients in a responsible, compliant manner you need commercial efforts …

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Carla Kim & Hans Clevers talks on organoids at #ISSCR2015

June 26, 2015 February 1, 2021 / By Heather Main / 4 Comments

Organoids are pretty big in stem cells right now with the last couple of years having attracted a lot of media attention on mini lungs, mini brains, mini kidneys, mini guts and more, giving the impression that scientists know how to specify and organise cells into mini functional organs in the lab. Organoids have become …

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Overview of Yamanaka Talk at #ISSCR2015 by Heather Main

June 25, 2015 February 1, 2021 / By Heather Main / 1 Comment

The day of plenary is the most enjoyable in my view including at ISSCR 2015 on the first day with a Yamanaka talk. You don’t need to make the choice between sessions and the judgement on the viability of shifting sessions versus staying put and listening to the slightly less relevant. ISSCR 2015 plenary was, …

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Search for a paper

The publicly available medical literature database PubMed can be found here. I recommend if you are doing a search for a stem cell paper on a disease of you interest that you plug into the search box the following: stem cells[title] AND XXXX In this case delete XXXX and put in the name of the …

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250,000-fold oversight on 3-person IVF mitochondrial transfer?

June 23, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

Remember the debate over so-called 3-person IVF? The goal of this technology, also referred to as mitochondrial transfer and 3-parent IVF, is to prevent mitochondrial disease through nuclear transfer in oocytes or one-cell embryos. The resulting genetically modified (GM) human embryos and ultimately children if it works could have dodged mitochondrial disease, but also could have serious or …

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Nugget Markets: no GMO policy, but ‘Non-GMO’ labeling common

June 11, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

My favorite grocery store here in Davis, California is Nugget Market. Our family shops at the various Nugget stores in the area fairly often. We like the food and the friendly service. I’ve been noticing not just at Nugget, but at some other stores too that the word “GMO” is popping up more. Both the actual …

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Will bioengineered body parts cost an arm and a leg?

June 4, 2015 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 3 Comments

The idea that we could bioengineer new human body parts to replace old, faulty ones is exciting, and such parts could include limbs, digits, or even entire organs. Such replacements might be produced using stem cells, 3-D printers, and other rapidly evolving, cutting edge technologies. Sci-fi is becoming a reality. Remember in Star Wars when …

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