Reports are out that a scientist in China has been working to make a CRISPR baby for some time and supposedly has made twin genetically modified babies. I see this work as unethical and dangerous. Just a couple years ago when I published my book GMO Sapiens on potential use of CRISPR in a heritable manner …
Why CRISPR baby production (if it happened) was unethical & dangerous Read More »
It’s an odd confluence of events this week that (A) the Nuffield Council, an ethics think tank, gives a thumbs up in a new report to heritable human genetic modification that would probably include using CRISPR in the same week that (B) a new paper reports that CRISPR can cause unpredictable genomic damage and several other concerning reports …
Mixed Nuffield Council Report Too Aspirational on Human Genetic Modification Read More »
It’s germline, heritable human CRISPR time, right? Wrong. But the particularly enthusiastic supporters of heritable human CRISPR often cite hypothetical benefits in glowing terms, but either don’t mention risks or strongly downplay them. These fans also tend to leave alternative, proven and safe technologies such as preimplantation genetic diagnosis (PGD) out of the discussion or …
Countering that Pro-Heritable Human CRISPR WSJ Piece Read More »
Are designer babies made using CRISPR or other genetic modification technologies closer to reality today? If so, what exactly should we do about it? Researchers can use CRISPR to genetically modify just about any organism or its cells, but targeting humans is the subject of the most intense discussion including using CRISPR in the human germline …
CRISPR, human genetic modification, & a needed course correction Read More »
Campaigns are underway in several European countries against the possible use of genetic modification in humans to make designer babies and one has a distinctly anti-CRISPR tone. For example, in France a group is pushing an anti-GM baby campaign and the same kind of thing is going on in Switzerland, which I blogged about recently. In …
First anti-CRISPR political campaign is born in Europe Read More »
Editor’s note. Caroline Simons attended both the April 28th (see her report on that here) and 29th Paris meetings on human gene editing/genetic modification. Today, we have her in depth report on the April 29th meeting. I have posted her piece in full with only minor edits. If you are in a rush you can …
In Depth Report from April 29th Paris Human Gene Edit Meeting Read More »
It’s exciting that the reviews are starting to come in on my new book, GMO Sapiens, on human genetic modification including CRISPR. Here is one from The Scientist and the book was recommended by Scientific American. Reviews from individual authors and scientists are below. “GMO Sapiens could not be more timely. New technologies like CRISPR-Cas9 gene …
Reviews of my new book GMO Sapiens on #CRISPR & human modification Read More »
With the approval today of the use of CRISPR in human embryos, the UK continues its recent trend toward a more permissive regulatory policy on human genetic modification. There are both risks and scientific benefits that come along with this trend. Last year the UK approved an experimental technology with the goal of preventing the …
CRISPR embryo OK signals ongoing liberal UK trend on human modification Read More »
What were the top 10 stem cell stories of the year? What were the biggest news and science headlines in the stem cell field in 2015, whether good or bad? Below are mine. What are your top 10 stem cell stories of the past year? Let us know in the comments. Organoids explode. Stem cell-based …
I’ve written extensively about the potential use of CRISPR in humans, including in particular in the germline where it would lead to heritable genetic modifications. Research using CRISPR in human embryos strictly for research purposes (not reproduction) is proceeding and in the case of non-viable embryos, such work has already been published (e.g. here), but …