Search Results for: jun takahashi

What are induced pluripotent stem cells or IPS cells?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or iPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too. This may manifest both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as …

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Grading my 20 stem cell predictions for 2020

Knoepfler-The-Niche-stem-cell-blog-predictions-2020

Each year I metaphorically try to look into a crystal ball for stem cell predictions for the coming year and I did so for 2020, but the COVID-19 pandemic threw a monkey wrench into my predictions. It actually kind of blew some up. It also raised some interesting questions and dilemmas. For instance, do many …

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20 predictions for stem cells & regenerative medicine in 2018

stem-cell-crystal-ball-300x3001

Every year I look into my stem cell crystal ball and make predictions for our field including regenerative medicine. Well, I don’t really look into a crystal ball, but I try to use a combination of what I’m hearing through the grapevine, stuff I’m reading, some info that is not yet in the public domain, …

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Highlights of ISSCR2017 – A Biomedical Engineer’s Perspective

Agnes-Soos

ISSCR meeting review By Agnes Soos Amid the hustle and bustle of downtown Boston, nearly four thousand researchers and exhibitors gathered for the 15th Annual ISSCR Meeting. With presentations from over thirty plenary lectures, and dozens of others featured in concurrent sessions and the daily Innovation Showcases, there definitely was no shortage of exciting research …

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How risky are stem cell trials for Parkinson’s beginning in China?

Brain-PET-scan, stem cells

New human clinical trials using derivatives of pluripotent stem cells in China for Parkinson’s Disease (PD) have raised expectations and some eyebrows. PD is a neurodegenerative condition, sometimes diagnosed or followed by PET scans such as the one at left, characterized by loss of dopaminergic neurons leading to severe and sometimes life-threatening symptoms. Pluripotent stem …

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Are iPS cells being rushed to the clinic or has their time come?

The iPS cell field has run fast and furious over the past 6 years reaching a big milestone surprisingly quickly on Monday with Shinya Yamanaka winning the Nobel Prize. But is  the field going too fast? In August I argued that iPS cells are not quite ready for primetime (i.e. clinical trial studies). Now in …

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