Search Results for: rmat

Big change for stem cell field with FDA quickly issuing RMATs

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Humacyte-e1493998220584

The 21st Century Cures Act has some important regenerative medicine language in it. One part of that was attempting to accelerate FDA review of promising investigation regenerative medicine therapies. The mechanism for this was a new designation called Regenerative Advanced Therapy, now renamed Regenerative Medicine Advanced Therapy (RMAT) Designation. I don’t think anyone was sure […]

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Is transactional science kicking transformative science’s butt?

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Science

What kind of scientist are you and do you engage in transactional science? I suspect that all of us scientists like to think that most of the work that we do is transformative and that we are a transformative scientist. In science we hear quite a lot about the importance of transformative, innovative science. But can

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Transformative idea for peer review: reviewing & grading the reviewers

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Do you feel frustrated with the current peer review system in science? I have an idea that might help and it involves the revolutionary idea of reviewer accountability. In other words, authors and grant writers in essence review their reviewers. I’ve made this all the easier for you with templates that you can simply and

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Dr Lookgood, dermatologist to the stars, gets FDA warning letter

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Dr-LookGood1

If you ever had a really bad day, March 13, 2012 might have been just such a bad day for one Dr. Steven Victor, aka “Dr LookGood”, because he received an official warning letter from the FDA. Why? Dr. Victor, who reportedly greets each patient with the catch phrase “You look so much more beautiful than your picture”, is

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Weekly reads: grow a spine, China clears MSCs, Denise Richards, stem cell soups

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Notochord, growing a spine.

If you tell a scientist that they should be growing a spine, they might take you literally. For instance, if you say this because you want a scientist to show some courage and speak out about something difficult, instead they might try to make an actual human spine in a lab. We’ll start there this

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Perspectives as Charles Brenner challenges David Sinclair on longevity claims

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Charles Brenner, David Sinclair

Professor Charles Brenner of City of Hope does great research, but I also applaud his efforts against longevity hype. Recently, Brenner and James Timmons publicly questioned some of the work of Harvard Professor David Sinclair. It’s a notable case of academics intensely disagreeing in the public space. Background While it’s interesting, it’s also a somewhat

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Weekly reads: intermittent fasting and stem cells, vet warning, blastemas

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intermittent fasting and stem cells

Intermittent fasting must be good for stem cells, right? It’s not so clear. Like many things in biology, intermittent fasting can have seemingly opposite effects. Before we get into that, the news of the week is that the FDA approved Mesoblast’s Ryoncil MSC drug for some cases of pediatric GvHD. This has sparked lively discussion.

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