Search Results for: scnt

Mitalipov Nature pub review: IPSC & SCNT for mitochondrial disease

February 1, 2021 / By / 6 Comments
Mitalipov-IPSC-paper

In a new, thought-provoking paper today in Nature, Shoukhrat Mitalipov and a multi-institutional team report a significant advance toward potential novel ways to treat mitochondrial diseases. What are these illnesses? Mitochondrial diseases are rare, but devastating disorders caused by genetic mutations. Today they are largely impossible to treat in meaningful ways other than palliative care. Some …

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Cloning is cloned again: New Nature Paper is 3rd on Human SCNT

February 1, 2021 / By
Yamada-Extended-Data-SCNT

A new human therapeutic cloning paper is out today, the third in a matter of months. This one is from the lab group of Dr. Dieter Egli published in Nature demonstrating production of nuclear transfer embryonic stem cells (NT-ESCs) from an adult human somatic donor via somatic cell nuclear transfer (SCNT). This human SCNT paper follows …

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The main challenges for SCNT cloning of human embryonic stem cells

February 1, 2021 / By / 1 Comment
human-cloning1

It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human embryonic stem cells (hESC). The first such work was published last year by Mitalipov’s group from OHSU. This second paper to produce so-called nuclear transfer hESC (NT-hESC) made the important advance to show that it could …

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Adult human therapeutic cloning of embryonic stem cells by SCNT

February 1, 2021 / By / 4 Comments
Human-SCNT1

An international team of stem cell scientists has replicated human therapeutic cloning to make embryonic stem cells via somatic cell nuclear transfer (SCNT). The team was led by Drs. Dong Ryul Lee of CHA Stem Cell Institute in Korea and Robert Lanza of Advanced Cell Technology (ACT) and reported the advance in the Chung, et …

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Jeanne Loring on Woo Suk Hwang Approved Patent of SCNT ESCs

February 1, 2021 / By / 10 Comments
Hwang-Mitalipov

If you’ve been paying attention to the stem cell world, you’ll remember Woo Suk Hwang, who nearly derailed the future of stem cell research by very publically proclaiming that he had made human embryonic stem cells by somatic cell nuclear transfer (SCNT). No, this has nothing to do with Shoukhrat Mitalipov’s report of successful generation …

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Why all the fuss about SCNT-derived ES cell paper?

February 1, 2021 / By / 1 Comment

This past week a paper came out in Nature that reported the successful production of human ES cells using somatic cell nuclear transfer (SCNT) technology. It is no exaggeration to say that this paper generated massive international media coverage, in part because of the links between this technology and the potential for human cloning, both …

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Take our poll on the new triploid SCNT-derived ES cells

February 1, 2021 / By

New human ES cell lines have been made using the technique of somatic cell nuclear transfer (SCNT). The new ES cells lines are genetically abnormal in that they have three sets of chromosomes instead of two. Two experts, Bob Lanza of ACT and Miodrag Stojkovic of University of Kragujevac in Serbia both are quoted by Nature News …

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Key Mayo Clinic stem cell webpage is overexuberant & outdated

March 30, 2024 / By / 2 Comments
The Mayo Clinic.

The Mayo Clinic does some great research on stem cells and regenerative medicine. However, at times I’ve felt that a few Mayo researchers are overexuberant. This mainly relates to certain not-yet-proven stem cell and related offerings. Fitting with that perception, the Mayo website also has some inaccurate stem cell content that leans toward overstating things. …

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Defining epigenetic reprogramming, cellular reprogramming & rejuvenation

September 20, 2023 / By / Leave a Comment
epigenetic reprogramming

Epigenetic reprogramming is a term used in cell biology that is increasingly ending up in news stories too. Unfortunately, some folks, especially in the cellular rejuvenation and anti-aging space, are getting this term and other things confused. Just to start off, epigenetic reprogramming does not specifically mean cellular rejuvenation. The goal of today’s post is …

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Human cloning is more likely now but would you take the big risks?

September 8, 2021 / By / 3 Comments
human cloning

I’ve been following the research related to human cloning now for more than a decade. Is human cloning more possible at this point? How do we even define such cloning? Did you know there are two types? The goal of this post is to educate you and in the process answer such questions. What’s in …

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