Search Results for: scnt

Mitalipov Nature pub review: IPSC & SCNT for mitochondrial disease

Mitalipov-IPSC-paper

In a new, thought-provoking paper today in Nature, Shoukhrat Mitalipov and a multi-institutional team report a significant advance toward potential novel ways to treat mitochondrial diseases. What are these illnesses? Mitochondrial diseases are rare, but devastating disorders caused by genetic mutations. Today they are largely impossible to treat in meaningful ways other than palliative care. Some …

Mitalipov Nature pub review: IPSC & SCNT for mitochondrial disease Read More »

Cloning is cloned again: New Nature Paper is 3rd on Human SCNT

Yamada-Extended-Data-SCNT

A new human therapeutic cloning paper is out today, the third in a matter of months. This one is from the lab group of Dr. Dieter Egli published in Nature demonstrating production of nuclear transfer embryonic stem cells (NT-ESCs) from an adult human somatic donor via somatic cell nuclear transfer (SCNT). This human SCNT paper follows …

Cloning is cloned again: New Nature Paper is 3rd on Human SCNT Read More »

The main challenges for SCNT cloning of human embryonic stem cells

human-cloning1

It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human embryonic stem cells (hESC). The first such work was published last year by Mitalipov’s group from OHSU. This second paper to produce so-called nuclear transfer hESC (NT-hESC) made the important advance to show that it could …

The main challenges for SCNT cloning of human embryonic stem cells Read More »

Adult human therapeutic cloning of embryonic stem cells by SCNT

Human-SCNT1

An international team of stem cell scientists has replicated human therapeutic cloning to make embryonic stem cells via somatic cell nuclear transfer (SCNT). The team was led by Drs. Dong Ryul Lee of CHA Stem Cell Institute in Korea and Robert Lanza of Advanced Cell Technology (ACT) and reported the advance in the Chung, et …

Adult human therapeutic cloning of embryonic stem cells by SCNT Read More »

Jeanne Loring on Woo Suk Hwang Approved Patent of SCNT ESCs

Hwang-Mitalipov

If you’ve been paying attention to the stem cell world, you’ll remember Woo Suk Hwang, who nearly derailed the future of stem cell research by very publically proclaiming that he had made human embryonic stem cells by somatic cell nuclear transfer (SCNT). No, this has nothing to do with Shoukhrat Mitalipov’s report of successful generation …

Jeanne Loring on Woo Suk Hwang Approved Patent of SCNT ESCs Read More »

Why all the fuss about SCNT-derived ES cell paper?

This past week a paper came out in Nature that reported the successful production of human ES cells using somatic cell nuclear transfer (SCNT) technology. It is no exaggeration to say that this paper generated massive international media coverage, in part because of the links between this technology and the potential for human cloning, both …

Why all the fuss about SCNT-derived ES cell paper? Read More »

Take our poll on the new triploid SCNT-derived ES cells

New human ES cell lines have been made using the technique of somatic cell nuclear transfer (SCNT). The new ES cells lines are genetically abnormal in that they have three sets of chromosomes instead of two. Two experts, Bob Lanza of ACT and Miodrag Stojkovic of University of Kragujevac in Serbia both are quoted by Nature News …

Take our poll on the new triploid SCNT-derived ES cells Read More »

What are embryonic stem cells & where do they come from?

Knoepfler lab stem cells

What are embryonic stem cells and how are they obtained? My lab has been doing research on embryonic stem cells for more than 14 years. You’ve come to the right place for expert answers on these very intriguing cells. What’s in this article Where do embryonic stem cells come from? | SCNT or cloning stem cells …

What are embryonic stem cells & where do they come from? Read More »

Where do stem cells come from? Expert answers

axolotol, where do stem cells come from?

We often talk about stem cells but there are some pretty basic, important questions that often go unanswered like ‘where do stem cells come from?’ The Niche It’s a more complicated and interesting question than you might think, and some of the answers point to novel ways in which stem cells may be used to …

Where do stem cells come from? Expert answers Read More »

Ian Wilmut, who cloned Dolly, opens up about his Parkinson’s Disease

Ian-Wilmut

One of the most famous living biological scientists, Sir Ian Wilmut, just announced that he has Parkinson’s Disease. I wish him the best in dealing with this illness. Wilmut is very well-known for having cloned the first mammal, Dolly the Sheep. This work followed on the earlier breakthrough by Sir John Gurdon of cloning the …

Ian Wilmut, who cloned Dolly, opens up about his Parkinson’s Disease Read More »