Search Results for: stem cell biotech

More Liveyon links to exosome Awakening film include potential relative

Awakening-film-marketing-screenshot

A new film-commercial entitled Awakening pitches unproven exosomes and has already been possibly tied to the troubled stem cell supplier firm Liveyon, but now it seems that the links go far deeper including a possible relative of Liveyon leader John Kosolcharoen. Even so, Kosolcharoen (pictured with another Liveyon leader Alan Gaveck below in a web …

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Heads up on Hui Yang, another potential aspiring CRISPR baby researcher

-Yui-Hang

Making a CRISPR baby is a controversial idea to even propose now for many reasons, yet even after He Jiankui’s train wreck some people have seemed eager to try it including apparently a scientist whose name perhaps many readers here are not so familiar with in this context: Professor Hui Yang. ‘CRISPR baby guys’ Is …

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FDA Regenerative Medicine Advanced Therapy RMAT designations jump to 36

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This post includes my updated list of firms/products that have received FDA regenerative medicine advanced therapy designation or RMAT, which are in the public domain. The numbers really jumped in the last month. I’m assuming for the purposes of this resource page that all self-reports are accurate. Note that the links embedded into the firm …

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Magenta Therapeutics Good News-Bad News Trial Data

Magenta

Magenta Therapeutics is a biotech company with a portfolio including stem cell products. Their most well known investigational drug product is an expanded umbilical cord stem cell product called MGTA-456, an “ex-Novartis” product. Magenta just released new trial data on MGTA-456, which I see as a case of good news-bad news, and investors seem to …

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Mulling over latest CRISPR tumult, this one from Nat Biot pub on DNA lesions

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If it seems to you like dramatic cautionary tales about CRISPR accompanied by all sorts of media are coming at us more frequently, it’s not your imagination. In the latest yesterday, it was reported in a new paper led by Allan Bradley that CRISPR-Cas9 results in sometimes large-scale chromosomal lesions at or even away from the …

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Updated FDA granted RMAT List (85)

FDA-RMAT

Today’s post includes a list of firms/products that have self-reported that they have received FDA regenerative medicine advanced therapy designation or RMAT. Sometimes people call these “r mat” with a space. As of December 12, 2023 there are 85 RMATs in the public domain. I also include FDA data on RMAT submissions via an FDA RMAT resource …

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7 tech hurdles to human germline CRISPR

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Human germline CRISPR raises major bioethical considerations, but what about technical issues? Setting aside the many ethical issue about the general idea of human modification itself, could this really work? Yes in theory it could, but there are some very tough technological challenges that could and likely would cause failures or unacceptable outcomes at many steps …

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DNA Ahead Game & More Struts Its Stuff

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Editor’s note: this is a guest post from Dr. Semenow on her new educational DNA game that also invokes stem cells. She has the remarkable distinction of having been the first woman who was a science Ph.D. student at Caltech. Stay tuned for my coming interview with her on her experiences in science. Her Kickstarter campaign …

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Interview with Fredrik Lanner who is CRISPR’ing healthy human embryos

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In the past year there has been a great deal of attention given to the potential use of CRISPR-Cas9 for gene editing in human embryos. An important recent development, described in a new NPR article by Rob Stein, is the use of CRISPR-Cas9 in healthy human embryos for developmental biology research by assistant professor Fredrik …

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Gaetan Burgio New Data & Theory on NgAgo versus CRISPR

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By Gaetan Burgio CRISPR/Cas9 genome editing has dramatically changed our way to perform biological experiments. While highly efficient and easy to use, one limitation with CRISPR/Cas9 mediated genome editing technology is the occurrence of off-target effects and the restriction of the PAM recognition sequence. Many modifications from the original system have been proposed to improve …

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