August 4, 2020

The Niche

Knoepfler lab stem cell blog


4 min read

Before the two STAP cell papers were published in Nature in January of 2014, much of the same data was reportedly submitted as single papers to other high-profile journals including Science. In these cases, the proto-STAP papers as we might call them were rejected. But why? Until now we largely could only speculate. However, the reviews of the 2012 proto-STAP manuscript at Science can now be read at Retraction Watch. As a result of reading the Science reviews, today we know what the reviewers at Science thought …Read More

2 min read

Nikkei is reporting that the RIKEN internal attempt to replicate so-called STAP (acid bath) cells has failed. Update: apparently, although RIKEN calls the efforts preliminary, the team tried to make STAP an amazing 22 times and 22 times it failed. The rumors for weeks in the stem cell gapevine that RIKEN itself could not get STAP to work, even with the help of Dr. Haruko Obokata, have been confirmed by Nikkei. Obokata was first author on both Nature STAP papers, which were retracted. One of …Read More

4 min read

What’s the deal with Brigham and Women’s Hospital or Harvard Medical School when it comes to the retracted STAP cell papers? I was just writing yesterday in part about how we haven’t really heard anything (news, statements, etc.) from those places about the whole STAP cell mess. In contrast, in Japan and at RIKEN there has been a non-stop flood of news and developments involving STAP. Now today I’ve heard from a source that senior STAP cell paper author, Dr. Charles Vacanti, will be stepping down …Read More

3 min read

In some ways it’s hard to imagine that it was only just over 6 months ago that Nature published the two STAP papers by a collaborative team of Japanese and American researchers. It feels like years have gone by since then because so much has happened related to the STAP mess including the retraction of the papers and the tragic death of one of the STAP authors, Dr. Yoshiki Sasai, last week. Where does the STAP story go from here? Is it over? In a way, …Read More