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The Niche

Knoepfler lab stem cell blog

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3-parent baby

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FDA chides US doc who genetically modified human embryo in reported 3-person IVF

August 4, 2017 Paul Knoepfler 1

The FDA sent a stern letter today to Dr. John Zhang, PhD, MD, the physician who last year created a genetically modified human embryo in the U.S. and then exported it to Mexico where he self-reported creating a genetically modified baby boy. […]

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CRISPR, human genetic modification, & a needed course correction

June 26, 2017 Paul Knoepfler 9

Are designer babies made using CRISPR or other genetic modification technologies closer to reality today? If so, what exactly should we do about it? Researchers can use CRISPR to genetically modify just about any organism or its cells, but targeting humans […]

cesar-palacios-gonzalez

Mitochondrial Replacement Techniques, the Mexican Case

September 30, 2016 Paul Knoepfler 0

By César Palacios-Gonzalez  Earlier this week New Scientist broke the news that the first baby born after Maternal Spindle Transfer is already five months old, and even more, he seems to be doing well. Even when John Zhang’s team has achieved […]

john-zhang-with-3-person-ivf-baby

First 3-person IVF baby born via “rogue” experiment at Mexico clinic?

September 27, 2016 Paul Knoepfler 5

Today we got the first report of a baby being born via so-called “3-person IVF”, sometimes called 3-parent IVF, in which the DNA of three people contribute to an offspring. Before discussing this further I have to emphasize that we need […]

Stem Cell Predictions

Stem cell predictions top 20 list for 2016

January 4, 2016 Paul Knoepfler 1

What will the new year have in store for stem cells? 2016 promises to have many striking stem cell developments. Below are my top 20 stem cell predictions for what is to come this year in no particular order. Share your […]

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