3-parent IVF

New Herbert lab Nature paper reinforces mitochondrial replacement Achilles heel

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Today a new Nature paper from Dr. Mary Herbert’s group in the UK has found a key problem with mitochondrial replacement therapy that fits with data from others. The goal of preventing mitochondrial disease using various kinds of genome transfer technologies is a noble one, but mitochondrial replacement therapy has faced a number of technological …

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UK should freeze mitochondrial replacement as Egli paper ID’s serious problem

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An important new Cell Stem Cell paper from Dieter Egli’s lab points to an inherent, serious problem with so-called 3-person IVF or mitochondrial replacement technology that warrants putting an immediate hold on all efforts to use it in humans. I have pasted the graphical abstract from the paper below. For years a few of us scientists and …

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Monday, March 2: My Reddit AMA on 3-Person IVF – Mitochondrial Transfer

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On Monday, I’ll be doing another Reddit AMA, this time on 3-person IVF also known as 3-parent IVF, mitochondrial transfer, 3-parent babies, etc. You can see the upcoming AMAs including mine listed in the right sidebar here. Mine will start at 10AM PST/1PM EST. I hope to discuss with a wide audience all the key …

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UK OKs 3-Person IVF: Perspectives

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With the House of Lords vote yesterday, the UK officially became the only country in the world to have legalized human genetic modification via 3-Person IVF. The point of this “mitochondrial transfer” or “3-person IVF” technology is not directly to genetically modify humans specifically, but it still will lead to that result in any case. …

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UK Surgeon General Calls My Concerns on 3-person IVF “Bunk”

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What is one to do when the equivalent of the Surgeon General of the UK calls one’s concerns about something, in this case 3-person IVF, “bunk”? It sure gave me some pause. What’s going on? First, some brief background. The debate over 3-person IVF/mitochondrial transfer technology has been getting more heated. The epicenter for the discussion …

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Nature Biased News Coverage of 3-Person IVF

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NatureNews is a science news outlet so I’ve been wondering what the heck the deal is with their strongly biased news coverage of the mitochondrial transfer 3-person IVF technology debate. By way of context, I like NatureNews and am a regular reader, but their coverage of the mitochondrial transfer debate has been completely one-sided and inaccurate. Their …

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Myths about 3-person IVF mitochondrial transfer

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It’s been somewhat of a helter-skelter time for the new technology often referred to as 3-person IVF or mitochondrial transfer as the UK considers whether to legalize this experimental technology for use in humans. I believe that this technology is not ready now for use in humans and for more background on why as well …

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Poll results: solid support, but desire for more data before 3-parent baby tech moves forward in humans

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I ran a poll asking readers of this blog about their view of 3-parent IVF also known as mitochondrial transfer technology. The poll got 166 responses over a few days. The results are in and they are surprising to me at least. They trend toward some level of support rather than opposition to approval of …

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