June 1, 2020

The Niche

Knoepfler lab stem cell blog

ABCD plan human gene editing

7 min read

What really happened at the DNA level in the experiments in that high-profile CRISPR of human embryos paper from a team led by Shoukhrat Mitalipov at OHSU? Is the team right that they successfully conducted CRISPR of human embryos to correct a mutant gene, as they reported in their Ma, et al. Nature paper? Or is the Egli, et al. preprint that came out later in response to the Ma paper more likely to be correct in their implied argument that something else very probably happened instead? We …Read More

3 min read

More CRISPR’d human embryos, but this time in America? MIT Tech Review is reporting that Oregon scientist Shoukhrat Mitalipov has used CRISPR on human embryos in his lab in the US. Apparently a paper is in the works on this. While details are sketchy and some specifics remain to be clarified to be sure of what’s the deal here, this Tech Review report appears generally accurate based on what I’ve heard so this appears to be the first reported use of CRISPR on human …Read More