advanced cell technology Archives

WAFSF stem cell vision talks: Hinton, Tsukamoto, Klassen, Takahashi

November 18, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 6 Comments

Recently I was at the World Alliance Forum in San Francisco (WAFSF), a great meeting on stem cells and regenerative medicine. WAFSF had some excellent talks and I saw one session on the use of stem cells to treat vision impairment that was particularly striking. World Alliance Forum in San Francisco (WAFSF) This session’s all-star lineup included Drs. David …

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Stem Cell Person of the Year Award: Only 2 Days Left To Vote

October 20, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

In two days the voting will end to pick the top 12 finalists for Stem Cell Person of the Year 2014 Award. You can vote here. From the finalists I will have the tough decision of picking the winner. Check out who’s in the top 12 now and who the top few vote getters are. Will someone surge …

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Advanced Cell Technology pub: Trial for Macular Degeneration

October 14, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 8 Comments

The stem cell biotech Advanced Cell Technology (ACT) reported new, positive data in a paper in Lancet from their clinical trials using retinal pigmented epithelial cells (RPEs) made from human embryonic stem cells (hESC) for treatment of different forms of macular degeneration (MD). The paper was entitled “Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related …

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Stem Cell Person of the Year 2014 Award: Vote To Choose 12 Finalists

October 8, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

Nominations have closed and we have more than two dozen nominations for Stem Cell Person of the Year 2014. It’s an exciting, diverse group including some news faces as well as nominees from years past as well. Happy Stem Cell Day! You can now vote for your choice for the top finalists in the poll …

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BioTime’s Cell Cure Files IND with FDA for ES cell AMD therapy

October 6, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 2 Comments

Stem cell biotech BioTime announced the news today that its subsidiary Cell Cure Neurosciences (Cell Cure) has filed an IND with the FDA for an embryonic stem (ES) cell-based therapy for Dry age-related macular degeneration (AMD). The product to be tested is OpRegen, which the company indicates is “the first IND for an ES cell-based …

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Where I Do The Ice Bucket Challenge & Who Did I Challenge?

August 25, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

I was challenged to do the Ice Bucket Challenge by Roman Reed. I did it yesterday and can see it was mighty cold! Total shock, but fun. It sure wakes you up. Yeah, we have a drought but I did the big splash with tons of ice. I did the challenge in honor of patients …

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Interview with Bob Lanza on new ACT MSCs for MS paper

June 9, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

I did a brief email Q&A interview with Dr. Bob Lanza of Advanced Cell Technology (ACT) on their new hES MSCs pre-clinical data for Multiple Sclerosis. I discussed the paper itself in a concise review yesterday here. Thanks to Dr. Lanza for doing the interview. 1. Were you surprised at the fact that the therapeutic …

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Advanced Cell Technology (ACT) Revs Up Pre-Clinical Studies for MS

June 8, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

There is more good news from leading stem cell biotech Advanced Cell Technology (ACT) on preclinical rodent studies using stem cells to treat mice with an MS-like condition. They published a new paper in the journal Stem Cell Reports entitled “Human ESC-Derived MSCs Outperform Bone Marrow MSCs in the Treatment of an EAE Model of …

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The main challenges for SCNT cloning of human embryonic stem cells

April 21, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 1 Comment

It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human embryonic stem cells (hESC). The first such work was published last year by Mitalipov’s group from OHSU. This second paper to produce so-called nuclear transfer hESC (NT-hESC) made the important advance to show that it could …

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Adult human therapeutic cloning of embryonic stem cells by SCNT

April 17, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

An international team of stem cell scientists has replicated human therapeutic cloning to make embryonic stem cells via somatic cell nuclear transfer (SCNT). The team was led by Drs. Dong Ryul Lee of CHA Stem Cell Institute in Korea and Robert Lanza of Advanced Cell Technology (ACT) and reported the advance in the Chung, et …

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