August 14, 2020

The Niche

Knoepfler lab stem cell blog

anti-aging

3 min read

Over the weekends I try to catch up on more diverse reading and sometimes come up with a list of stuff I want to get to during this time, but I also put together weekend reads usually on Fridays as a kind of TGIF on The Niche for the wider audience here. So here’s the weekend reads for this Friday the 13th including some wacky stuff at the end. Anti-Aging efforts got some play in the media including this LA Times piece. Here’s the …Read More

3 min read

Can we humans grow healthy new brain cells as adults and during later aging? The answer to this question is a big deal because it could have major impact on aging. Those hoped-for new brain cells could keep our brains functionally younger. Who doesn’t want to slow down the aging of their brain, right? Slowing down aging of the brain via new cell growth more broadly would have major impacts on society. Researchers have gone back and forth on this over years. Fairly long …Read More

3 min read

It’s stem cell day! Or more accurately, it is stem cell awareness day. It’s a good time to think about where our field stands and where we’ll be in 10 years. Below, I’ve outlined 10 for 10: 10 things to ponder about stem cells in a 10-year timeframe. Approved Therapies. How many new stem cell therapies will be approved as safe and effective in 10 years? I hope at least 10! These may include proven transformative regenerative medicine treatments for macular degeneration, Type 1 …Read More

4 min read

A new Cell paper from Juan Carlos Izpisua Berlmonte’s group has made headlines about anti-aging across the globe because it suggests that the four core induced pluripotent stem cell (IPSC) factors use by Shinya Yamanaka to make IPSC can reverse aging. I’ve pasted the graphical abstract from the paper below and done a quick journal club style overview based on a quick skim of the paper. Some of the media headlines are rather dramatic on this story. For instance, in a story on it over at STAT …Read More