September 28, 2020

The Niche

Knoepfler lab stem cell blog

best stem cell book

2 min read

Type 1 Diabetes is a huge global problem. Where are the solutions that would compliment or replace insulin therapy for diabetics? There haven’t been too many that have gotten very far, which makes the news of a potential stem cell-based therapy moving along in the pipeline all the more exciting. ViaCyte (see more posts here, here, here, here on the company) just got FDA approval for its investigational new drug (IND), paving the way to start a combined Phase I/II clinical trial. ViaCyte was …Read More

4 min read

What might be some natural stem cell boosts? How might we all increase the number or helpful activities of our own stem cells? If possible isn’t that a better, simpler, & safer idea than getting a transplant of stem cells? Think of it as preventative medicine via stem cells. Note that this post was updated in May 2020. It’s not a sure thing by any means. And, yeah, it is not as simple as asking for a free or super boost in your Jamba …Read More

4 min read

It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human embryonic stem cells (hESC). The first such work was published last year by Mitalipov’s group from OHSU. This second paper to produce so-called nuclear transfer hESC (NT-hESC) made the important advance to show that it could be done using adult and even old human somatic cells. This is a reproducible technology, which is very important. However, key challenges and concerns remain for human therapeutic cloning …Read More

2 min read

Sometimes you think you know a person and they suddenly surprise you by doing something so new that it is shocking or by taking on a new personality. Cells can be that way too. In my book on stem cells, Stem Cells: An Insider’s Guide (you can buy it here on Amazon–it’s very affordable–or also here at the publisher’s site for some international buyers) published last year, great scientific illustrator, Taylor Seamount, and I came up with a new adaptation (see image above) of a classic model …Read More