California Institute for Regenerative Medicine

Polls: will California approve Prop 14 to fund CIRM again? Should it?

Knoepfler-The-Niche-stem-cell-blog-predictions-2020

Back at the beginning of the year I surveyed you readers here on The Niche about the future of CIRM and whether California voters would approve more funding for it in November. That funding effort is now on the ballot as Proposition 14. A month earlier late in 2019 in my yearly 20 predictions for …

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Stem cell cha-ching! CIRM has economic impact in billions, 56K+ jobs

CIRM-impact

We here in California have been fortunate to have our own stem cell and regenerative medicine agency called CIRM, standing for the California Institute for Regenerative Medicine. How much has CIRM helped the California economy and has it had broader economic impacts outside of California? How will that impact its future? CIRM has been around …

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Muddy waters: stem cell clinic calls itself CIRM & docuseries sparks controversy

CIRM-or-CIRM

We’re seeing more muddy waters in the stem cell universe. A chiropractic stem cell and alternative medicine clinic has popped up calling itself, of all things, CIRM. On another front, an already controversial docuseries set to air tomorrow combines interviews with prominent academic stem cell scientists and unproven stem cell clinic folks, muddying the waters. …

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The future of California stem cell research & CIRM

stem-cell-eye-chart-2020

The four words “California stem cell research” go nicely together and I hope they will continue to resonate in a special way to people around the world in the coming decade. We are at a crossroads for stem cell research in California as the original form of the California Stem Cell Agency (CIRM) winds down. …

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Poll on refunding CIRM on eve of informational legislative hearing

CIRM-

Our California stem cell agency, CIRM, started as a baby even before I came to California in 2006 to start my lab here at UC Davis School of Medicine, but now CIRM or to use its full name the California Institute for Regenerative Medicine is I’d say a full-grown, mature adult at about age 13 …

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Stem cell good news: Spinal Cord Injury Trial, CIRM, Grants, & More

Jan-Nolta-stem-cell-good-news-2

Stem cell good news time…and more will be coming later this week. The stem cell and regenerative medicine world sometimes feels chaotic because so much is going on both on the positive and negative sides of things. There is a whirlwind of activity and developments, and a tendency sometimes within our arena to just avoid …

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2017 stem cell predictions: score card at 1/2-way point

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In December of each year I make a list of stem cell predictions for the coming year, and I made 20 such predictions for 2017 so I’m wondering how I’m doing so far on these now that it’s June. Below is my work-in-progress scorecard for these so far. Positive news from Asterias on trial for stem cell-based …

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Upbeat prospects for some California clinical trial efforts from CIRM

Asterias-cells

Over at the California Stem Cell Report, David Jensen is reporting on some good news from CIRM for California on the stem cell clinical trial front. Stem cell biotechs Asterias and Capricor have stem cell trials supported by 20+ million in CIRM funding each and have been hitting milestones. These trials are progressing and so far have good safety …

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Early, but encouraging data from Asterias on stem cells for spinal cord injury

Asterias

As I posted recently, Asterias Biotherapeutics has had good early safety results so far in its historic stem cell trial for spinal cord injury and now the company presented some early, encouraging hints at efficacy.  However, a caveat here is that this is not an RCT (randomized controlled trial). Ed Wirth, CMO of Asterias, presented the …

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The backstory on my opinion piece in SF Chronicle critical of CIRM lobbying

CIRM-2.0

Today an opinion piece that I wrote about CIRM was published in the San Francisco Chronicle. The unusual element here is that the article is critical of CIRM. More specifically I raised concerns about a recent political trend at CIRM under its new President Randy Mills lobbying for dramatically weaker stem cell regulatory oversight. The Chronicle piece was first posted …

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