January 17, 2021

The Niche

Trusted stem cell blog & resources

Cancer

2 min read

Yesterday I ran a cancer stem cells meeting here at UC Davis School of Medicine. We had some great speakers and over 150 participants including our outstanding keynote speaker, Dr. Jeremy Rich, Director of Stem Cell Research at the Cleveland Clinic. One of the ideas percolating through the meeting was that during cancer development, there is a tremendous amount of plasticity. Cancer is not a linear process that starts with a stem cell gone bad and proceeds through defined steps A-Z. It is more …Read More

5 min read

There is a kind of invisible cultural wall between patients such as cancer patients and biomedical scientists like me, but this wall does not have to exist and indeed it is a negative wall as patients, scientists, doctors, agencies, and advocates can achieve far more together than apart. But the wall is surprisingly strong. Last year when I was diagnosed with prostate cancer, that wall was broken for me. I was suddenly both scientist and patient at the same time. Now I am both …Read More

3 min read

Cancer is a class of diseases that are intimately linked to stem cells. In fact, I would go so far as to call some types of cancer cells and stem cells, cousins. This concept, of a tight relationship between stem and cancer cells, is under intense investigation but at the same time it is something that many stem cell scientists would rather not think about. It is simply reality. A wide variety of cancers exhibit gene expression profiles that share modules with highly pluripotent …Read More